product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TXNIP (D5F3E) Rabbit mAb
catalog :
14715
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D5F3E
reactivity :
human, mouse
application :
western blot, other, western blot knockout validation
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 3c
Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
  • other; mouse; 1:1000; loading ...; fig 5a
Eckrich J, Frenis K, Rodriguez Blanco G, Ruan Y, Jiang S, Bayo Jimenez M, et al. Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice. Redox Biol. 2021;46:102063 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7b
Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller Schön S, et al. Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Basic Res Cardiol. 2021;116:31 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6c
Zhou W, Shao W, Zhang Y, Liu D, Liu M, Jin T. Glucagon-like peptide-1 receptor mediates the beneficial effect of liraglutide in an acute lung injury mouse model involving the thioredoxin-interacting protein. Am J Physiol Endocrinol Metab. 2020;319:E568-E578 pubmed publisher
  • western blot; human; loading ...; fig 1e
Li H, Lan J, Wang G, Guo K, Han C, Li X, et al. KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation. J Exp Clin Cancer Res. 2020;39:12 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4g
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s20a, s20b
Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed publisher
Karmi O, Sohn Y, Marjault H, Israeli T, Leibowitz G, Ioannidis K, et al. A Combined Drug Treatment That Reduces Mitochondrial Iron and Reactive Oxygen Levels Recovers Insulin Secretion in NAF-1-Deficient Pancreatic Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Li Y, Tong K, Lu J, Lin J, Li Z, Sang Y, et al. PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. Aging (Albany NY). 2020;12:2507-2529 pubmed publisher
Dong L, Reljic B, Cheung J, Ng E, Lindqvist L, Elefanty A, et al. In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose. Cell Death Differ. 2019;: pubmed publisher
Ruiz L, Gurlo T, Ravier M, Wojtusciszyn A, Mathieu J, Brown M, et al. Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment. Cell Death Dis. 2018;9:600 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.