product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Ras (G12D Mutant Specific) (D8H7) Rabbit mAb
catalog :
14429
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D8H7
reactivity :
human, mouse
application :
western blot, immunohistochemistry
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2b, 3e
  • western blot; human; loading ...; fig 4f
Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed publisher
  • western blot; human; loading ...; fig s2b
Waters A, Ozkan Dagliyan I, Vaseva A, Fer N, Strathern L, Hobbs G, et al. Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Sci Signal. 2017;10: pubmed publisher
  • western blot; human; fig s6
Gusscott S, Jenkins C, Lam S, Giambra V, Pollak M, Weng A. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS ONE. 2016;11:e0161158 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 2a
Rowald K, Mantovan M, Passos J, Buccitelli C, Mardin B, Korbel J, et al. Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth. Cell Rep. 2016;15:2679-91 pubmed publisher
Swidnicka Siergiejko A, Gomez Chou S, Cruz Monserrate Z, Deng D, Liu Y, Huang H, et al. Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53. Oncogene. 2017;36:3149-3158 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.