product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HIF-1alpha (D2U3T) Rabbit mAb
catalog :
14179
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2U3T
reactivity :
human, mouse, rat, swine
application :
western blot
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig s3a
Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed publisher
  • western blot; rat; 1:2000; loading ...; fig 4a, s3
  • western blot; human; 1:2000; loading ...; fig s3
Thiele R, Osuru H, Paila U, Ikeda K, Zuo Z. Impact of inflammation on brain subcellular energetics in anesthetized rats. BMC Neurosci. 2019;20:34 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s2
Chakraborty A, Laukka T, Myllykoski M, Ringel A, Booker M, Tolstorukov M, et al. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science. 2019;363:1217-1222 pubmed publisher
  • western blot; mouse; loading ...; fig 6c
Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
  • western blot; human; loading ...; fig 4a
Wang M, Li G, Yang Z, Wang L, Zhang L, Wang T, et al. Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer. Oncotarget. 2017;8:8083-8094 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
  • western blot; swine; loading ...; fig 3a
Ren W, Yin J, Xiao H, Chen S, Liu G, Tan B, et al. Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection. Front Immunol. 2016;7:685 pubmed publisher
  • western blot; human; 1:1000; fig 5d
Mughal A, Grieg Z, Skjellegrind H, Fayzullin A, Lamkhannat M, Joel M, et al. Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells. Mol Cancer. 2015;14:160 pubmed publisher
Hart P, Kenny H, Grassl N, Watters K, Litchfield L, Coscia F, et al. Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk. Cell Rep. 2019;29:4086-4098.e6 pubmed publisher
Huang Z, Li G, Zhang Z, Gu R, Wang W, Lai X, et al. β2AR-HIF-1α-CXCL12 signaling of osteoblasts activated by isoproterenol promotes migration and invasion of prostate cancer cells. BMC Cancer. 2019;19:1142 pubmed publisher
Labuschagne C, Cheung E, Blagih J, Domart M, Vousden K. Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization. Cell Metab. 2019;30:720-734.e5 pubmed publisher
Yin Y, Zhang Q, Zhao Q, Ding G, Wei C, Chang L, et al. Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition. Biomed Res Int. 2019;2019:6595437 pubmed publisher
Li L, Wang L, Li J, Fan Z, Yang L, Zhang Z, et al. Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer. Cancer Res. 2018;78:1779-1791 pubmed publisher
Bernard K, Logsdon N, Benavides G, SANDERS Y, Zhang J, Darley Usmar V, et al. Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation. J Biol Chem. 2018;293:1218-1228 pubmed publisher
Braverman J, Stanley S. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B. J Immunol. 2017;199:1805-1816 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.