product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-YAP (Ser397) (D1E7Y) Rabbit mAb
catalog :
13619
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1E7Y
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3a
Li B, He J, Lv H, Liu Y, Lv X, Zhang C, et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019;129:1167-1179 pubmed publisher
  • western blot; human; loading ...; fig 1f
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 3a
Greenhough A, Bagley C, Heesom K, Gurevich D, Gay D, Bond M, et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med. 2018;10: pubmed publisher
  • western blot; human; loading ...; fig 9a
Kapil S, Sharma B, Patil M, Elattar S, Yuan J, Hou S, et al. The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Oncotarget. 2017;8:26515-26531 pubmed publisher
  • western blot; human; loading ...; fig 1g
Zhu G, Chen Y, Zhang X, Wu Q, Zhao Y, Chen Y, et al. 12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT. Sci Rep. 2017;7:44940 pubmed publisher
  • western blot; human; loading ...; fig 2g
Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher
  • western blot; human; loading ...; fig 3d
Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  • western blot; human; loading ...; fig 4
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  • western blot; mouse; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher
  • western blot; human; fig 6
Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher
  • immunocytochemistry; mouse
  • immunocytochemistry; rat
  • immunocytochemistry; human
Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
Ito T, Nakamura A, Tanaka I, Tsuboi Y, Morikawa T, Nakajima J, et al. CADM1 associates with Hippo pathway core kinases; membranous co-expression of CADM1 and LATS2 in lung tumors predicts good prognosis. Cancer Sci. 2019;110:2284-2295 pubmed publisher
Hao F, Xu Q, Zhao Y, Stevens J, Young S, Sinnett Smith J, et al. Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells. Mol Cancer Res. 2017;15:929-941 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.