product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NF-kappaB1 p105/p50 (D4P4D) Rabbit mAb
catalog :
13586
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D4P4D
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; 1:200; loading ...; fig 4c
  • western blot; human; loading ...; fig 4d
Tsoi H, Man E, Chau K, Khoo U. Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer. Cancers (Basel). 2021;13: pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig s2g
  • western blot; human; 1:1000; loading ...; fig s2c
Szymura S, Bernal G, Wu L, Zhang Z, Crawley C, Voce D, et al. DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy. BMC Biol. 2020;18:32 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Beug S, Cheung H, Sanda T, St Jean M, Beauregard C, Mamady H, et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 2019;12: pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Choi Y, Park S, Sun Y, Yoo J, Pudupakam R, Foo S, et al. Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis. Nat Microbiol. 2019;4:429-437 pubmed publisher
  • western blot; human; fig 1a
Makhov P, Naito S, Haifler M, Kutikov A, Boumber Y, Uzzo R, et al. The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma. Cell Death Dis. 2018;9:374 pubmed publisher
  • immunohistochemistry; rat; 1:200; loading ...; fig 2i
Eros K, Magyar K, Deres L, Skazel A, Riba A, Vamos Z, et al. Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats. PLoS ONE. 2017;12:e0174401 pubmed publisher
  • western blot; human; 1:1000; fig s15
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
  • western blot; mouse; fig 8
Cinti A, De Giorgi M, Chisci E, Arena C, Galimberti G, Farina L, et al. Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro. PLoS ONE. 2015;10:e0141933 pubmed publisher
Sobuz S, Sato Y, Yoshizawa T, Karim F, Ono K, Sawa T, et al. SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran. Biochim Biophys Acta Mol Cell Res. 2019;1866:1355-1367 pubmed publisher
Qian F, Hu Q, Tian Y, Wu J, Li D, Tao M, et al. ING4 suppresses hepatocellular carcinoma via a NF-κB/miR-155/FOXO3a signaling axis. Int J Biol Sci. 2019;15:369-385 pubmed publisher
Braverman J, Stanley S. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B. J Immunol. 2017;199:1805-1816 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.