product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p63-alpha (D2K8X) XP Rabbit mAb
catalog :
13109
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2K8X
reactivity :
human, mouse
application :
western blot, immunohistochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 1c
  • chromatin immunoprecipitation; human; 1:1000; loading ...; fig 1d
Hegde G, de la Cruz C, Giltnane J, Crocker L, Venkatanarayan A, Schaefer G, et al. NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma. elife. 2019;8: pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig 1b
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s2
Marshall C, Beeler J, Lehmann B, González Ericsson P, Sanchez V, Sanders M, et al. Tissue-specific expression of p73 and p63 isoforms in human tissues. Cell Death Dis. 2021;12:745 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3b
DeLaForest A, Kohlnhofer B, Franklin O, Stavniichuk R, Thompson C, Pulakanti K, et al. GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium. Cell Mol Gastroenterol Hepatol. 2021;12:1391-1413 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1f
Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed publisher
  • western blot; human; loading ...; fig 1F
Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed publisher
  • western blot; human; 1:1000; fig 2
Palombo R, Porta G, Bruno E, Provero P, Serra V, Neduri K, et al. OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development. Aging (Albany NY). 2015;7:928-36 pubmed
Beeler J, Marshall C, Gonzalez Ericsson P, Shaver T, Santos Guasch G, Lea S, et al. p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS ONE. 2019;14:e0218458 pubmed publisher
Lin Shiao E, Lan Y, Welzenbach J, Alexander K, Zhang Z, Knapp M, et al. p63 establishes epithelial enhancers at critical craniofacial development genes. Sci Adv. 2019;5:eaaw0946 pubmed publisher
Song E, Min S, Oyelakin A, Smalley K, Bard J, Liao L, et al. Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018;8:14043 pubmed publisher
Zhuang Z, Xie N, Hu J, Yu P, Wang C, Hu X, et al. Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma. Oncotarget. 2017;8:21954-21973 pubmed publisher
Hamanaka R, Mutlu G. PFKFB3, a Direct Target of p63, Is Required for Proliferation and Inhibits Differentiation in Epidermal Keratinocytes. J Invest Dermatol. 2017;137:1267-1276 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.