| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 4c
| Correia de Sousa M, Calo N, Sobolewski C, Gjorgjieva M, Clement S, Maeder C, et al. Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. Cancers (Basel). 2021;13: pubmed publisher |
- western blot; human; loading ...; fig 3g
| Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher |
- western blot; human; loading ...; fig 4g
| Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1a, 2a
| Xu X, Shen X, Wang J, Feng W, Wang M, Miao X, et al. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021;20:e13465 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Zheng Z, Li C, Shao G, Li J, Xu K, Zhao Z, et al. Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI. Cell Death Dis. 2021;12:754 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4g
| Chi X, Luo W, Song J, Li B, Su T, Yu M, et al. Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice. Cell Death Dis. 2021;12:604 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3f, 3h
| Carter P, Schnell U, Chaney C, TONG B, Pan X, ye J, et al. Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma. J Clin Invest. 2021;131: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1i
| Tamura T, Kodama T, Sato K, Murai K, Yoshioka T, Shigekawa M, et al. Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation. J Clin Invest. 2021;131: pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 4c, 4j
| Dai M, Yan G, Wang N, Daliah G, Edick A, Poulet S, et al. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy. Nat Commun. 2021;12:3055 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3e
| Yang C, Liu Q, Chen Y, Wang X, Ran Z, Fang F, et al. Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve. Commun Biol. 2021;4:534 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7c
| Zheng T, Liu X, Li X, Wang Q, Zhao Y, Li X, et al. Dickkopf-1 promotes Vascular Smooth Muscle Cell proliferation and migration through upregulating UHRF1 during Cyclic Stretch application. Int J Biol Sci. 2021;17:1234-1249 pubmed publisher |
- western blot; human; loading ...; fig s4c
| Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, et al. PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. Cell Death Dis. 2020;11:506 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 4b
- western blot; human; 1:1000; loading ...; fig 4c
| Wen X, Wan J, He Q, Wang M, Li S, Jiang M, et al. p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer. Signal Transduct Target Ther. 2020;5:81 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
| Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, et al. Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature. 2020;580:524-529 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Guo Q, Quan M, Dong J, Bai J, Wang J, Han R, et al. The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy. Theranostics. 2020;10:4422-4436 pubmed publisher |
- western blot; human; 1:500; fig 5d
| An L, Nie P, Chen M, Tang Y, Zhang H, Guan J, et al. MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway. J Exp Med. 2020;217: pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1s3d
| Sivaraj K, Dharmalingam B, Mohanakrishnan V, Jeong H, Kato K, Schröder S, et al. YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells. elife. 2020;9: pubmed publisher |
- western blot; human; loading ...; fig 6e
| Yin L, Li W, Xu A, Shi H, Wang K, Yang H, et al. SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway. EBioMedicine. 2020;51:102596 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 2e
| Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed publisher |
- western blot; mouse; loading ...; fig 1b
| Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher |
- western blot; human; 1:1000; fig 4a
| Ho L, Skiba N, Ullmer C, Rao P. Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018;59:1969-1984 pubmed publisher |
- western blot; rat; 1:500; loading ...; fig 1c
| Chen B, Liu G. WWC3 inhibits intimal proliferation following vascular injury via the Hippo signaling pathway. Mol Med Rep. 2018;17:5175-5183 pubmed publisher |
- western blot; human; 1:500; fig 3b
| Zheng X, Dong Q, Zhang X, Han Q, Han X, Han Y, et al. The coiled-coil domain of oncogene RASSF 7 inhibits hippo signaling and promotes non-small cell lung cancer. Oncotarget. 2017;8:78734-78748 pubmed publisher |
- western blot; human; loading ...; fig 9a
| Kapil S, Sharma B, Patil M, Elattar S, Yuan J, Hou S, et al. The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Oncotarget. 2017;8:26515-26531 pubmed publisher |
- western blot; human; loading ...; fig 2g
| Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1B
- western blot; mouse; 1:1000; loading ...; fig 1(S1A)
| Grove M, Kim H, Santerre M, Krupka A, Han S, Zhai J, et al. YAP/TAZ initiate and maintain Schwann cell myelination. elife. 2017;6: pubmed publisher |
- western blot; mouse; 1:1000; fig s7a
| Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed publisher |
- western blot; human; loading ...; fig 4
| Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed |
- immunohistochemistry - paraffin section; human; 1:500
- western blot; human; 1:1000; loading ...; fig s2a
| Chen Y, Xu J, Skanderup A, Dong Y, Brannon A, Wang L, et al. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nat Commun. 2016;7:13131 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:2000; fig 5B
| Georgescu M, Gagea M, Cote G. NHERF1/EBP50 Suppresses Wnt-?-Catenin Pathway-Driven Intestinal Neoplasia. Neoplasia. 2016;18:512-23 pubmed publisher |
- western blot; mouse; loading ...; fig 4b
- western blot; human; loading ...; fig 4a
| Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher |
- western blot; human; fig 2
| Wang D, Wu Y, Huang J, Wang W, Xu M, Jia J, et al. Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance. Chin J Cancer. 2016;35:47 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2c
| Jia Q, Zhou W, Yao W, Yang F, Zhang S, Singh R, et al. Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices. Oncogenesis. 2016;5:e220 pubmed publisher |
- western blot; human; fig 5a
| Cheng J, Chang H, Liu P, Leung P. Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. Cell Signal. 2016;28:643-51 pubmed publisher |
- western blot; human; fig 6
| Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher |
- immunocytochemistry; mouse; 1:2000; fig 3
| Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri J. A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway. Lab Invest. 2015;95:765-80 pubmed publisher |
| Morgan E, Patterson M, Ryder E, Lee S, Wasson C, Harper K, et al. MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer. PLoS Pathog. 2020;16:e1008624 pubmed publisher |
| Malouf G, Flippot R, Dong Y, DiNatale R, Chen Y, Su X, et al. Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers. Sci Rep. 2020;10:701 pubmed publisher |
| Wu Y, Shen L, Liang X, Li S, Ma L, Zheng L, et al. Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression. Cancer Med. 2019;: pubmed publisher |
| Hao F, Xu Q, Wang J, Yu S, Chang H, Sinnett Smith J, et al. Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. PLoS ONE. 2019;14:e0216603 pubmed publisher |
| Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, et al. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Mol Cell. 2019;73:7-21.e7 pubmed publisher |
| Gill M, Christova T, Zhang Y, Gregorieff A, Zhang L, Narimatsu M, et al. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis. Nat Commun. 2018;9:3510 pubmed publisher |
| Meliambro K, Wong J, Ray J, Calizo R, Towne S, Cole B, et al. The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics. J Biol Chem. 2017;292:21137-21148 pubmed publisher |
| Hao F, Xu Q, Zhao Y, Stevens J, Young S, Sinnett Smith J, et al. Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells. Mol Cancer Res. 2017;15:929-941 pubmed publisher |
| Mori S, Takeuchi T, Ishii Y, Yugawa T, Kiyono T, Nishina H, et al. Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor. J Virol. 2017;91: pubmed publisher |
