product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CaMKII
catalog :
12716
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D21E4
reactivity :
human, mouse, rat
application :
western blot
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 6c
Cheng J, Dong Y, Ma J, Pan R, Liao Y, Kong X, et al. Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology. Sci Adv. 2021;7: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1f
Chang N, Yeh C, Lin Y, Kuo K, Fong I, Kounis N, et al. Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a, 4c
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt S, Vieira Saecker A, et al. NLRP3 inflammasome activation drives tau pathology. Nature. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2k
Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, et al. The mechanosensitive Piezo1 channel is required for bone formation. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4f
Amal H, Gong G, Gjoneska E, Lewis S, Wishnok J, Tsai L, et al. S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. Transl Psychiatry. 2019;9:44 pubmed publisher
  • western blot; human; loading ...; fig s3c
Ren D, Dai Y, Yang Q, Zhang X, Guo W, Ye L, et al. Wnt5a induces and maintains prostate cancer cells dormancy in bone. J Exp Med. 2019;216:428-449 pubmed publisher
  • western blot; mouse; loading ...; fig 4c, 4d, 4e
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, et al. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. Cell Metab. 2019;29:979-992.e4 pubmed publisher
  • western blot; human; 1:1000; loading ...
Li Q, Ye L, Zhang X, Wang M, Lin C, Huang S, et al. FZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/β-catenin signaling. Cancer Lett. 2017;402:166-176 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Prasad A, Ketsawatsomkron P, Nuno D, Koval O, Dibbern M, Venema A, et al. Role of CaMKII in Ang-II-dependent small artery remodeling. Vascul Pharmacol. 2016;87:172-179 pubmed publisher
  • western blot; mouse; 1:1000; fig 3h
Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed publisher
  • western blot; mouse; 1:1000; fig s4c
Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
  • western blot; rat; fig 5
Goto A, Egawa T, Sakon I, Oshima R, Ito K, Serizawa Y, et al. Heat stress acutely activates insulin-independent glucose transport and 5'-AMP-activated protein kinase prior to an increase in HSP72 protein in rat skeletal muscle. Physiol Rep. 2015;3: pubmed publisher
  • western blot; human
D Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
  • western blot; mouse; fig 5
Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed publisher
Zhao Q, Wang W, Cui J. Melatonin enhances TNF-α-mediated cervical cancer HeLa cells death via suppressing CaMKII/Parkin/mitophagy axis. Cancer Cell Int. 2019;19:58 pubmed publisher
Partida G, Fasoli A, Fogli Iseppe A, Ogata G, Johnson J, Thambiaiyah V, et al. Autophosphorylated CaMKII Facilitates Spike Propagation in Rat Optic Nerve. J Neurosci. 2018;38:8087-8105 pubmed publisher
Nagappan Chettiar S, Johnson Venkatesh E, Umemori H. Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation. J Biol Chem. 2018;293:12026-12042 pubmed publisher
Pahng A, Paulsen R, McGinn M, Edwards K, Edwards S. Neurobiological Correlates of Pain Avoidance-Like Behavior in Morphine-Dependent and Non-Dependent Rats. Neuroscience. 2017;366:1-14 pubmed publisher
Strong C, Schoepfer K, Dossat A, Saland S, Wright K, Kabbaj M. Locomotor sensitization to intermittent ketamine administration is associated with nucleus accumbens plasticity in male and female rats. Neuropharmacology. 2017;121:195-203 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.