| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; human; 1:100; loading ...; fig 1a
- western blot; human; loading ...; fig 1c
| Wang Y, Liu I, Chen K, Wu H. NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck. Oncogenesis. 2021;10:59 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s9c
| Pattwell S, Arora S, Cimino P, Ozawa T, Szulzewsky F, Hoellerbauer P, et al. A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways. Nat Commun. 2020;11:2977 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 4b
| Hegde G, de la Cruz C, Giltnane J, Crocker L, Venkatanarayan A, Schaefer G, et al. NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 1a
| Kennedy S, Han J, Portman N, Nobis M, Hastings J, Murphy K, et al. Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. Breast Cancer Res. 2019;21:43 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 2e
| Jeong J, Choi J, Kim W, Dann P, Takyar F, Gefter J, et al. Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells. J Biol Chem. 2019;294:887-901 pubmed publisher |
- western blot; human; loading ...; fig s1b
| Fan P, Narzisi G, Jayaprakash A, Venturini E, Robine N, Smibert P, et al. YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. Proc Natl Acad Sci U S A. 2018;115:E6030-E6038 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1g
| Schumacher M, Hedl M, Abraham C, Bernard J, Lozano P, Hsieh J, et al. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death Dis. 2017;8:e2622 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2
| Alver T, Lavelle T, Longva A, Øy G, Hovig E, Bøe S. MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma. Oncotarget. 2016;7:55128-55140 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 6
| Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed publisher |
- western blot; human; loading ...; fig 4f
| Chung V, Tan T, Tan M, Wong M, Kuay K, Yang Z, et al. GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. Sci Rep. 2016;6:19943 pubmed publisher |
- western blot; human; 1:1000; fig 4b
| Ebbing E, Medema J, Damhofer H, Meijer S, Krishnadath K, van Berge Henegouwen M, et al. ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3. Oncotarget. 2016;7:10243-54 pubmed publisher |
- immunocytochemistry; human; fig 3
- western blot; human; fig 1
| Jeong J, VanHouten J, Dann P, Kim W, Sullivan C, Yu H, et al. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016;113:E282-90 pubmed publisher |
- immunocytochemistry; mouse; 1:100; fig 4
- western blot; mouse; 1:100; fig 1
| Sathyamurthy A, Yin D, Barik A, Shen C, Bean J, Figueiredo D, et al. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015;142:522-32 pubmed publisher |
| Li N, Xu Y, Zhang Y, Li G, Yu T, Yao R, et al. Biallelic ERBB3 loss-of-function variants are associated with a novel multisystem syndrome without congenital contracture. Orphanet J Rare Dis. 2019;14:265 pubmed publisher |
| Frazier N, Brand T, Gordan J, Grandis J, Jura N. Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation. Oncogene. 2019;38:1936-1950 pubmed publisher |
| Wege A, Chittka D, Buchholz S, Klinkhammer Schalke M, Diermeier Daucher S, Zeman F, et al. HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women. Breast Cancer Res. 2018;20:139 pubmed publisher |
| Freed D, Bessman N, Kiyatkin A, Salazar Cavazos E, Byrne P, Moore J, et al. EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell. 2017;171:683-695.e18 pubmed publisher |
