product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MDR1/ABCB1 (D3H1Q) Rabbit mAb
catalog :
12683
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3H1Q
reactivity :
human
application :
western blot, immunohistochemistry
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:200; loading ...; fig 4c
Pellegrini L, Bonfio C, Chadwick J, Begum F, Skehel M, Lancaster M. Human CNS barrier-forming organoids with cerebrospinal fluid production. Science. 2020;: pubmed publisher
  • western blot; human; loading ...
Debruyne D, Dries R, Sengupta S, Seruggia D, Gao Y, Sharma B, et al. BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells. Nature. 2019;572:676-680 pubmed publisher
  • western blot; human; loading ...; fig s2
Yan M, Wang J, Ren Y, Li L, He W, Zhang Y, et al. Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization. Cell Death Dis. 2019;10:204 pubmed publisher
  • western blot; human; loading ...; fig 5b
Ren H, Liu F, Huang G, Liu Y, Shen J, Zhou P, et al. Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma. Oncotarget. 2017;8:6718-6729 pubmed publisher
  • western blot; human; loading ...; fig 3h
Zhao X, Li L, Wang X, Fu R, Lv Y, Jin W, et al. Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0164752 pubmed publisher
Mun G, Choi E, Lee Y, Lee Y. Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1. Cell Death Dis. 2020;11:395 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.