product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PRMT4/CARM1 (3H2) Mouse mAb
catalog :
12495
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3H2
reactivity :
human, mouse
application :
immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section, ChIP-Seq, proximity ligation assay, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:2000; loading ...; fig 1c
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1b
  • immunoprecipitation; mouse; loading ...; fig 1c
Jamet S, Ha S, Ho T, Houghtaling S, Timms A, Yu K, et al. The Arginine Methyltransferase Carm1 is Necessary for Heart Development. G3 (Bethesda). 2022;: pubmed publisher
  • western blot knockout validation; human; 1:1000; loading ...; fig s1d
Yin S, Liu L, Brobbey C, PALANISAMY V, Ball L, Olsen S, et al. PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021;12:3444 pubmed publisher
  • proximity ligation assay; human; 1:1000; fig 4c
Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3d
  • immunoprecipitation; human; loading ...; fig 3c
Hiken J, McDonald J, Decker K, Sanchez C, Hoog J, VanderKraats N, et al. Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer. Oncogene. 2017;36:2319-2327 pubmed publisher
  • ChIP-Seq; mouse; loading ...; fig s6e
  • immunoprecipitation; mouse; loading ...; fig 4a
  • immunocytochemistry; mouse; loading ...; fig 4b
Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.