product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-DARPP-32 (Thr34) (D27A4) Rabbit mAb
catalog :
12438
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D27A4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - free floating section
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1c
Sun R, Tsunekawa T, Hirose T, Yaginuma H, Taki K, Mizoguchi A, et al. GABAB receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice. Sci Rep. 2021;11:19296 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:200; loading ...; fig 6a
Domi E, Xu L, Pätz M, Nordeman A, Augier G, Holm L, et al. Nicotine increases alcohol self-administration in male rats via a μ-opioid mechanism within the mesolimbic pathway. Br J Pharmacol. 2020;177:4516-4531 pubmed publisher
  • western blot; human; 1:500
Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  • western blot; mouse; 1:500 to 1:1000
Guibinga G, Barron N, Pandori W. Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome. PLoS ONE. 2014;9:e96575 pubmed publisher
Badimon A, Strasburger H, Ayata P, Chen X, Nair A, Ikegami A, et al. Negative feedback control of neuronal activity by microglia. Nature. 2020;: pubmed publisher
Engmann O, Giralt A, Gervasi N, Marion Poll L, Gasmi L, Filhol O, et al. DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nat Commun. 2015;6:10099 pubmed publisher
product information
SKU :
12438S
Product-Name :
Phospho-DARPP-32 (Thr34) (D27A4) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Western blot
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
32
Host :
Rabbit
Target :
DARPP-32 (Thr34) phosphate
Primary-Protein :
DARPP-32
Alt-Names :
DARPP-32,DARPP32,Dopamine- and cAMP-regulated neuronal phosphoprotein,FLJ20940,PPP1R1B,PPR1B,Protein phosphatase 1 regulatory subunit 1B,dopamine and cAMP regulated phosphoprotein,dopamine and cAMP-regulated neuronal phosphoprotein 32,protein phosphatase 1, regulatory (inhibitor) subunit 1B,protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.