product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NLRC4 (D5Y8E) Rabbit mAb
catalog :
12421
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D5Y8E
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2500; loading ...; fig 6b
Kucsera D, T xf3 th V, Gerg x151 D, V xf6 r xf6 s I, On xf3 di Z, G xf6 rbe A, et al. Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice. Front Physiol. 2021;12:609465 pubmed publisher
  • western blot; human; loading ...; fig s2b
Koh H, Kim Y, Kim J, Yun J, Jang K, Yang C. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα. PLoS Pathog. 2017;13:e1006126 pubmed publisher
Mehto S, Jena K, Nath P, Chauhan S, Kolapalli S, Das S, et al. The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mol Cell. 2019;73:429-445.e7 pubmed publisher
Su S, Zhao J, Xing Y, Zhang X, Liu J, Ouyang Q, et al. Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages. Cell. 2018;175:442-457.e23 pubmed publisher
Moghaddas F, Zeng P, Zhang Y, Schützle H, Brenner S, Hofmann S, et al. Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface. J Allergy Clin Immunol. 2018;142:1956-1967.e6 pubmed publisher
product information
SKU :
12421S
Product-Name :
NLRC4 (D5Y8E) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Rabbit
Target :
NLRC4
Primary-Protein :
NLRC4
Alt-Names :
CARD, LRR, and NACHT-containing protein,CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,Caspase recruitment domain-containing protein 12,Clan protein,ICE-protease activating factor,IPAF,Ice protease-activating factor,NLR family CARD domain-containing protein 4,NLR family, CARD domain containing 4,NLRC4,NOD-like receptor C4,caspase recruitment domain family, member 12,nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.