product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
YAP (1A12) Mouse mAb
catalog :
12395
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A12
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 9d
  • immunoprecipitation; human; 1:100; loading ...; fig 7b
  • western blot; human; 1:1000; loading ...; fig 3a
Lu J, Yang Y, Guo G, Liu Y, Zhang Z, Dong S, et al. IKBKE regulates cell proliferation and epithelial-mesenchymal transition of human malignant glioma via the Hippo pathway. Oncotarget. 2017;8:49502-49514 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 3c
Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s2a
Chen Y, Xu J, Skanderup A, Dong Y, Brannon A, Wang L, et al. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nat Commun. 2016;7:13131 pubmed publisher
  • proximity ligation assay; mouse; 1:100; loading ...; fig 5a
  • immunoprecipitation; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 1a
Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher
  • western blot; human; fig 4
Qi Y, Yu J, Han W, Fan X, Qian H, Wei H, et al. A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation. Nat Commun. 2016;7:ncomms11840 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 3b
Zhang L, Yu Z, Xian Y, Lin X. microRNA-497 inhibits cell proliferation and induces apoptosis by targeting YAP1 in human hepatocellular carcinoma. FEBS Open Bio. 2016;6:155-64 pubmed publisher
  • western blot; human; fig 7b
Cheng J, Chang H, Liu P, Leung P. Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. Cell Signal. 2016;28:643-51 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a-b
  • western blot; mouse; loading ...; fig 7i
Wang Y, Cui R, Zhang X, Qiao Y, Liu X, Chang Y, et al. SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma. Oncotarget. 2016;7:11284-98 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.