product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GFAP (D1F4Q) XP® Rabbit mAb
catalog :
12389
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1F4Q
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4d
Sahu M, Pazos Boubeta Y, Steinzeig A, Kaurinkoski K, Palmisano M, Borowecki O, et al. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Front Mol Neurosci. 2021;14:616178 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4c, 4e
Ferreira N, Gonçalves N, Jan A, Jensen N, van der Laan A, Mohseni S, et al. Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. Acta Neuropathol Commun. 2021;9:31 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s3a
Suzuki G, Imura S, Hosokawa M, Katsumata R, Nonaka T, Hisanaga S, et al. α-synuclein strains that cause distinct pathologies differentially inhibit proteasome. elife. 2020;9: pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5a
Yang F, Yang L, Wataya Kaneda M, Teng L, Katayama I. Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model. PLoS ONE. 2020;15:e0228204 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5d
  • western blot; mouse; 1:1000; loading ...; fig 4g
Bertrand L, Méroth F, Tournebize M, Leda A, Sun E, Toborek M. Targeting the HIV-infected brain to improve ischemic stroke outcome. Nat Commun. 2019;10:2009 pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 3g
Zhu C, Li B, Frontzek K, Liu Y, Aguzzi A. SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease. J Exp Med. 2019;216:743-756 pubmed publisher
  • immunohistochemistry; rat; 1:200; loading ...; fig 1d
Zhu B, Carmichael R, Solabre Valois L, Wilkinson K, Henley J. The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons. Biochem Biophys Res Commun. 2018;500:645-649 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 2d
Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 1g
Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, et al. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. Cell. 2018;172:409-422.e21 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4a
Zou J, Zhang B, Gutmann D, Wong M. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. Epilepsia. 2017;58:2053-2063 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s2b
Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, et al. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med. 2017;214:547-563 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6b
Sareddy G, Viswanadhapalli S, Surapaneni P, Suzuki T, Brenner A, Vadlamudi R. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017;36:2423-2434 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig S1c
Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Su X, Tan Q, Parikh B, Tan A, Mehta M, Sia Wey Y, et al. Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina. Invest Ophthalmol Vis Sci. 2016;57:3397-408 pubmed publisher
Xiao D, Zhang W, Wang Q, Li X, Zhang Y, Rasouli J, et al. CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology. Mol Ther Methods Clin Dev. 2021;20:755-764 pubmed publisher
Patel S, Hartley R, Wei X, Furnish R, Escobar Riquelme F, Bear H, et al. Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation. Neuro Oncol. 2020;22:381-392 pubmed publisher
Tu Z, Tan X, Li S, Cui J, Tu S, Jiang L. The therapeutic effect of controlled reoxygenation on chronic hypoxia-associated brain injury. Biol Open. 2019;8: pubmed publisher
Lippi S, Smith M, Flinn J. A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology. Front Aging Neurosci. 2018;10:382 pubmed publisher
Musi N, Valentine J, Sickora K, Baeuerle E, Thompson C, Shen Q, et al. Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell. 2018;17:e12840 pubmed publisher
Manzoni C, Mamais A, Dihanich S, Soutar M, Plun Favreau H, Bandopadhyay R, et al. mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Biosci Rep. 2018;38: pubmed publisher
Hernandes M, LASSEGUE B, Hilenski L, Adams J, Gao N, Kuan C, et al. Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain. J Neuroinflammation. 2018;15:45 pubmed publisher
Huang J, You X, Liu W, Song C, Lin X, Zhang X, et al. Electroacupuncture ameliorating post-stroke cognitive impairments via inhibition of peri-infarct astroglial and microglial/macrophage P2 purinoceptors-mediated neuroinflammation and hyperplasia. BMC Complement Altern Med. 2017;17:480 pubmed publisher
Grossman N, Bono D, Dedic N, Kodandaramaiah S, Rudenko A, Suk H, et al. Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields. Cell. 2017;169:1029-1041.e16 pubmed publisher
Minter M, Zhang C, Leone V, Ringus D, Zhang X, Oyler Castrillo P, et al. Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease. Sci Rep. 2016;6:30028 pubmed publisher
Haan N, Zhu B, Wang J, Wei X, Song B. Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury. J Neuroinflammation. 2015;12:109 pubmed publisher
product information
SKU :
12389P
Product-Name :
GFAP (D1F4Q) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Frozen)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Rabbit
Target :
GFAP
Primary-Protein :
GFAP
Alt-Names :
FLJ45472,GFAP,Glial fibrillary acidic protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.