product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PKR (D7F7) Rabbit mAb
catalog :
12297
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D7F7
reactivity :
human
application :
western blot, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3c
Shadle S, Zhong J, Campbell A, Conerly M, Jagannathan S, Wong C, et al. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS Genet. 2017;13:e1006658 pubmed publisher
  • western blot; human; loading ...; fig 3c
Carpentier K, Esparo N, Child S, Geballe A. A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists. PLoS Pathog. 2016;12:e1005966 pubmed publisher
  • western blot; human; fig 5
Pham A, Santa Maria F, Lahiri T, Friedman E, Marié I, Levy D. PKR Transduces MDA5-Dependent Signals for Type I IFN Induction. PLoS Pathog. 2016;12:e1005489 pubmed publisher
  • western blot; human; fig 5
Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher
  • western blot; human; fig 2
Burgess H, Mohr I. Cellular 5'-3' mRNA exonuclease Xrn1 controls double-stranded RNA accumulation and anti-viral responses. Cell Host Microbe. 2015;17:332-344 pubmed publisher
Burgess H, Pourchet A, Hajdu C, Chiriboga L, Frey A, Mohr I. Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics. 2018;8:71-81 pubmed publisher
Liot G, Zala D, Pla P, Mottet G, Piel M, Saudou F. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites. J Neurosci. 2013;33:6298-309 pubmed publisher
product information
SKU :
12297S
Product-Name :
PKR (D7F7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
74
Host :
Rabbit
Target :
PKR
Primary-Protein :
PKR
Alt-Names :
E2AK2,EIF2AK1,EIF2AK2,Eukaryotic translation initiation factor 2-alpha kinase 2,Interferon-induced, double-stranded RNA-activated protein kinase,Interferon-inducible RNA-dependent protein kinase,MGC126524,P1/eIF-2A protein kinase,PKR,PRKR,Protein kinase RNA-activated,double stranded RNA activated protein kinase,eIF-2A protein kinase 2,interferon-inducible elF2alpha kinase,p68 kinase,protein kinase, interferon-inducible double stranded RNA dependent
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.