product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LAMTOR4/C7orf59 (D6A4V) Rabbit mAb
catalog :
12284
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D6A4V
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:250; loading ...; fig 1c
Özkan N, Koppers M, van Soest I, van Harten A, Jurriens D, Liv N, et al. ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nat Commun. 2021;12:4493 pubmed publisher
  • western blot; mouse; loading ...; fig s6a
  • western blot; human; loading ...; fig s5c, s6b
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s1c
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher
Deng Y, Qin Y, Srikantan S, Luo A, Cheng Z, Flores S, et al. The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. Hum Mol Genet. 2018;27:1794-1808 pubmed publisher
Schweitzer L, Comb W, Bar Peled L, Sabatini D. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1. Cell Rep. 2015;12:1445-55 pubmed publisher
product information
SKU :
12284S
Product-Name :
LAMTOR4/C7orf59 (D6A4V) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
11
Host :
Rabbit
Target :
C7orf59
Primary-Protein :
LAMTOR4
Alt-Names :
C7orf59,LAMTOR4,LOC389541,late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.