product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Actin (8H10D10) Mouse mAb (HRP Conjugate)
catalog :
12262
clonality :
monoclonal
host :
mouse
conjugate :
HRP
clone name :
8H10D10
reactivity :
human, mouse, rat, dogs
application :
western blot
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 3s1c
Zhang H, Sathyamurthy A, Liu F, Li L, Zhang L, Dong Z, et al. Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice. elife. 2019;8: pubmed publisher
  • western blot; human; fig 3
Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed publisher
  • western blot; human; loading ...; fig 6c
Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed publisher
  • western blot; human; tbl 2
Bhargava A, Pelech S, Woodard B, Kerwin J, Maherali N. Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. elife. 2016;5: pubmed publisher
  • western blot; mouse; 1:2000; fig 2
Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
Lang X, Green M, Wang W, Yu J, Choi J, Jiang L, et al. Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11. Cancer Discov. 2019;9:1673-1685 pubmed publisher
Chau K, Shannon M, Fame R, Fonseca E, Mullan H, Johnson M, et al. Downregulation of ribosome biogenesis during early forebrain development. elife. 2018;7: pubmed publisher
Wan S, Sun X, Wu F, Yu Z, Wang L, Lin D, et al. Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensis. J Neuroinflammation. 2018;15:31 pubmed publisher
Lillo M, Nichols C, Perry C, Runke S, Krutilina R, Seagroves T, et al. Methylparaben stimulates tumor initiating cells in ER+ breast cancer models. J Appl Toxicol. 2017;37:417-425 pubmed publisher
Hung M, Leonard J. Stabilization of exosome-targeting peptides via engineered glycosylation. J Biol Chem. 2015;290:8166-72 pubmed publisher
Wright D, Renoir T, Smith Z, Frazier A, Francis P, Thorburn D, et al. N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease. Transl Psychiatry. 2015;5:e492 pubmed publisher
Burcham G, Cresswell G, Snyder P, Chen L, Liu X, Crist S, et al. Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis. Am J Pathol. 2014;184:3176-91 pubmed publisher
Logan R, Kong A, Krise J. Time-dependent effects of hydrophobic amine-containing drugs on lysosome structure and biogenesis in cultured human fibroblasts. J Pharm Sci. 2014;103:3287-96 pubmed publisher
Ueno T, Endo S, Saito R, Hirose M, Hirai S, Suzuki H, et al. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells. Oncol Res. 2013;21:155-64 pubmed publisher
Cai M, Liu P, Wei L, Wang J, Qi J, Feng S, et al. Atp6v1c1 may regulate filament actin arrangement in breast cancer cells. PLoS ONE. 2014;9:e84833 pubmed publisher
Gajdosechova L, Krskova K, Segarra A, Špolcová A, Suski M, Olszanecki R, et al. Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue. J Endocrinol. 2014;220:333-43 pubmed publisher
Zhou Q, Jiang L, Xu C, Luo D, Zeng C, Liu P, et al. Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis. Thromb Res. 2014;133:57-65 pubmed publisher
Killinger B, Shah M, Moszczynska A. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. J Neurochem. 2014;128:764-75 pubmed publisher
Li M, Yang Y, He Z, Zhou Z, Yang T, Guo P, et al. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X ch. Drug Metab Dispos. 2014;42:44-61 pubmed publisher
Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, et al. IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-? secretion and LPS-induced endotoxin shock. J Immunol. 2013;191:3913-21 pubmed publisher
Logan R, Kong A, Krise J. Evaluating the roles of autophagy and lysosomal trafficking defects in intracellular distribution-based drug-drug interactions involving lysosomes. J Pharm Sci. 2013;102:4173-80 pubmed publisher
Liao R, Jung J, Tchaicha J, Wilkerson M, Sivachenko A, Beauchamp E, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013;73:5195-205 pubmed publisher
Hu H, Li Z, Zhu X, Lin R, Lin J, Peng J, et al. Gua Lou Gui Zhi decoction suppresses LPS-induced activation of the TLR4/NF-?B pathway in BV-2 murine microglial cells. Int J Mol Med. 2013;31:1327-32 pubmed publisher
Balakrishnan B, Sen D, Hareendran S, Roshini V, David S, Srivastava A, et al. Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors. PLoS ONE. 2013;8:e53845 pubmed publisher
Bracarense A, Lucioli J, Grenier B, Drociunas Pacheco G, Moll W, Schatzmayr G, et al. Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets. Br J Nutr. 2012;107:1776-86 pubmed publisher
product information
SKU :
12262S
Product-Name :
β-Actin (8H10D10) Mouse mAb (HRP Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, Dg
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
45
Host :
Mouse
Target :
beta-Actin
Primary-Protein :
ACTB
Alt-Names :
ACTB,Actin, cytoplasmic 1,Actin, cytoplasmic 1, N-terminally processed,Beta-actin,PS1TP5-binding protein 1,PS1TP5BP1,actin, beta,beta actin,beta cytoskeletal actin
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.