product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Calreticulin (D3E6) XP® Rabbit mAb
catalog :
12238
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3E6
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig e6e
Liu X, Viswanadhapalli S, Kumar S, Lee T, Moore A, Ma S, et al. Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress. Nat Cancer. 2022;: pubmed publisher
  • western blot; human; loading ...; fig 1d
Mondal T, Shivange G, Tihagam R, Lyerly E, Battista M, Talwar D, et al. Unexpected PD-L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Mol Med. 2021;13:e12716 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 2b
  • immunohistochemistry - paraffin section; mouse; fig 6b
Luo X, Gong H, Gao H, Wu Y, Sun W, Li Z, et al. Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2. Cell Death Differ. 2021;: pubmed publisher
  • western blot; mouse; loading ...; fig 1f
Li Y, Ivica N, Dong T, Papageorgiou D, He Y, Brown D, et al. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020;11:4837 pubmed publisher
  • western blot; rat; loading ...; fig 1b, 3b
Herring S, Moon H, Rawal P, Chhibber A, Zhao L. Brain clusterin protein isoforms and mitochondrial localization. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 8d
Bagashev A, Sotillo E, Tang C, Black K, Perazzelli J, Seeholzer S, et al. CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum. Mol Cell Biol. 2018;38: pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig s8
Yang L, Wang L, Ketkar H, Ma J, Yang G, Cui S, et al. UBXN3B positively regulates STING-mediated antiviral immune responses. Nat Commun. 2018;9:2329 pubmed publisher
  • western blot; human; loading ...; fig 4c
Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5
Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  • western blot; mouse; fig 3g
  • western blot; rat; fig 3e
Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 6h
Cader M, Boroviak K, Zhang Q, Assadi G, Kempster S, Sewell G, et al. C13orf31 (FAMIN) is a central regulator of immunometabolic function. Nat Immunol. 2016;17:1046-56 pubmed publisher
  • western blot; mouse; fig 4
Berthoud V, Minogue P, Lambert P, Snabb J, Beyer E. The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses. J Biol Chem. 2016;291:17569-78 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig s1m
Krampitz G, George B, Willingham S, Volkmer J, Weiskopf K, Jahchan N, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A. 2016;113:4464-9 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2b
Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, et al. Dendritic cells combined with doxorubicin induces immunogenic cell death and exhibits antitumor effects for osteosarcoma. Oncol Lett. 2016;11:2169-2175 pubmed
  • western blot; human
Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed publisher
  • immunocytochemistry; human; 1:20; loading ...; fig 4b
Wada A, Takagi Y, Kono M, Morikawa T. Accuracy of a New Platelet Count System (PLT-F) Depends on the Staining Property of Its Reagents. PLoS ONE. 2015;10:e0141311 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed publisher
Chen J, Zou L, Lu G, Grinchuk O, Fang L, Ong D, et al. PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation. Cell Discov. 2022;8:52 pubmed publisher
Zhao M, Lu L, Lei S, Chai H, Wu S, Tang X, et al. Inhibition of Receptor Interacting Protein Kinases Attenuates Cardiomyocyte Hypertrophy Induced by Palmitic Acid. Oxid Med Cell Longev. 2016;2016:1451676 pubmed publisher
product information
SKU :
12238P
Product-Name :
Calreticulin (D3E6) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ca, cAMP and Lipid Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
55
Host :
Rabbit
Target :
calreticulin
Primary-Protein :
calreticulin
Alt-Names :
CALR,CRP55,CRT,CRTC,Calregulin,Calreticulin,ERp60,Endoplasmic reticulum resident protein 60,FLJ26680,HACBP,RO,SSA,Sicca syndrome antigen A (autoantigen Ro,autoantigen Ro,cC1qR,calreticulin),grp60
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.