product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Akt (Thr450) (D5G4) Rabbit mAb
catalog :
12178
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D5G4
reactivity :
human, mouse, rat, zebrafish
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3f
Lin K, Bieri G, Gontier G, Müller S, Smith L, Snethlage C, et al. MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling. PLoS Biol. 2021;19:e3001311 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3a
Guan J, Lin H, Xie M, Huang M, Zhang D, Ma S, et al. Higenamine exerts an antispasmodic effect on cold-induced vasoconstriction by regulating the PI3K/Akt, ROS/α2C-AR and PTK9 pathways independently of the AMPK/eNOS/NO axis. Exp Ther Med. 2019;18:1299-1308 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5g
Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher
  • western blot; human; fig 3
Huang W, Zhao H, Dong H, Wu Y, Yao L, Zou F, et al. High-mobility group box 1 impairs airway epithelial barrier function through the activation of the RAGE/ERK pathway. Int J Mol Med. 2016;37:1189-98 pubmed publisher
  • western blot; mouse; 1:1000; fig s4
Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  • western blot; zebrafish ; 1:1000; fig 4
Kearns C, Ravanelli A, Cooper K, Appel B. Fbxw7 Limits Myelination by Inhibiting mTOR Signaling. J Neurosci. 2015;35:14861-71 pubmed publisher
Maubant S, Tesson B, Maire V, Ye M, Rigaill G, Gentien D, et al. Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells. PLoS ONE. 2015;10:e0122333 pubmed publisher
Goel S, Chin E, Fakhraldeen S, Berry S, Beebe D, Alexander C. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts. J Biol Chem. 2012;287:16454-66 pubmed publisher
product information
SKU :
12178S
Product-Name :
Phospho-Akt (Thr450) (D5G4) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Akt1 (Thr450) phosphate/Akt2 (Thr451) phosphate/Akt3 (Thr447) phosphate
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.