product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MAPKAPK-2 (D1E11) Rabbit mAb
catalog :
12155
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1E11
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunoprecipitation
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 7d
Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher
  • western blot; human; fig 5c
Xu P, Zhou Z, Xiong M, Zou W, Deng X, Ganaie S, et al. Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway. PLoS Pathog. 2017;13:e1006266 pubmed publisher
Diaz Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al. In vitro characterization of the human segmentation clock. Nature. 2020;580:113-118 pubmed publisher
Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed publisher
Onodera Y, Teramura T, Takehara T, Itokazu M, Mori T, Fukuda K. Inflammation-associated miR-155 activates differentiation of muscular satellite cells. PLoS ONE. 2018;13:e0204860 pubmed publisher
Wang Q, Yan R, Pinnell N, McCarter A, Oh Y, Liu Y, et al. Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood. 2018;: pubmed publisher
Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, et al. Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation. Sci Rep. 2018;8:2021 pubmed publisher
Zheng Y, Wang Z, Ding X, Zhang W, Li G, Liu L, et al. A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma. Cancer Cell Int. 2018;18:6 pubmed publisher
Mack J, Mosqueiro T, Archer B, Jones W, Sunshine H, Faas G, et al. NOTCH1 is a mechanosensor in adult arteries. Nat Commun. 2017;8:1620 pubmed publisher
Court H, Ahearn I, Amoyel M, Bach E, Philips M. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol. 2017;216:4165-4182 pubmed publisher
Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, et al. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking. J Biol Chem. 2017;292:15964-15973 pubmed publisher
Fujiki K, Inamura H, Miyayama T, Matsuoka M. Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. J Biol Chem. 2017;292:7942-7953 pubmed publisher
Britton G, Ambler R, Clark D, Hill E, Tunbridge H, McNally K, et al. PKC? links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton. elife. 2017;6: pubmed publisher
Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
Ezratty E, Pasolli H, Fuchs E. A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol. 2016;214:89-101 pubmed publisher
Matulic M, Skelin J, Radić Kristo D, Kardum Skelin I, Grcevic D, Antica M. Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry A. 2015;87:129-36 pubmed publisher
Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed publisher
Harjes U, Bridges E, McIntyre A, Fielding B, Harris A. Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells. J Biol Chem. 2014;289:23168-76 pubmed publisher
Hagenbeek T, Wu X, Choy L, Sanchez Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and ?c/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed publisher
Yoshida R, Nagata M, Nakayama H, Niimori Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher
product information
SKU :
12155S
Product-Name :
MAPKAPK-2 (D1E11) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, B, Pg, (Hm, Dg, Hr)
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
47, 49 (Phosphorylated)
Host :
Rabbit
Target :
MAPKAPK-2
Primary-Protein :
MAPKAPK2
Alt-Names :
MAP kinase-activated protein kinase 2,MAPK-activated protein kinase 2,MAPK2,MAPKAP kinase 2,MAPKAPK-2,MAPKAPK2,MK2,mitogen-activated protein kinase-activated protein kinase 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.