product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Brn2/POU3F2 (D2C1L) Rabbit mAb
catalog :
12137
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2C1L
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, ChIP-Seq
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3f
  • chromatin immunoprecipitation; human; fig 5f
  • western blot; human; fig 3f
Hamm M, Sohier P, Petit V, Raymond J, Delmas V, Le Coz M, et al. BRN2 is a non-canonical melanoma tumor-suppressor. Nat Commun. 2021;12:3707 pubmed publisher
  • ChIP-Seq; human; 1:200; fig 4
  • immunocytochemistry; human; 1:500; fig 3
  • western blot; human; fig s4
Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed publisher
  • western blot; human; fig 6a
Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed publisher
Zhao G, Wei Z, Guo Y. MicroRNA-107 is a novel tumor suppressor targeting POU3F2 in melanoma. Biol Res. 2020;53:11 pubmed publisher
Sato T, Yoo S, Kong R, Sinha A, Chandramani Shivalingappa P, Patel A, et al. Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma. Cancer Res. 2019;79:6084-6100 pubmed publisher
Cox R, Calderon de Anda F, Mangoubi T, Yoshii A. Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects in Tsc-1-Suppressed Brain. Front Mol Neurosci. 2018;11:409 pubmed publisher
Zhang M, Ngo J, Pirozzi F, Sun Y, Wynshaw Boris A. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther. 2018;9:67 pubmed publisher
product information
SKU :
12137S
Product-Name :
Brn2/POU3F2 (D2C1L) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Chromatin Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
55
Host :
Rabbit
Target :
POU3F2/Brn2
Primary-Protein :
Oct7
Alt-Names :
BRN2,Brain-2,Brain-specific homeobox/POU domain protein 2,Brn-2,Nervous system-specific octamer-binding transcription factor N-Oct-3,OCT7,OTF-7,OTF7,Oct-7,Octamer-binding protein 7,Octamer-binding transcription factor 7,PO3F2,POU class 3 homeobox 2,POU domain, class 3, transcription factor 2,POU3F2,POUF3
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.