product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SGK1 (D27C11) Rabbit mAb
catalog :
12103
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D27C11
reactivity :
human, mouse, rhesus macaque
application :
western blot, immunohistochemistry - paraffin section, western blot knockout validation
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 4b, 1i
  • western blot; rhesus macaque; loading ...; fig 4b, 1i
Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer K, Cedillo L, et al. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. 2019;177:299-314.e16 pubmed publisher
  • western blot; human; loading ...; fig 7d
Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Du X, de Almeida P, Manieri N, de Almeida Nagata D, Wu T, Harden Bowles K, et al. CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1. Proc Natl Acad Sci U S A. 2018;115:E11731-E11740 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1h
  • western blot; human; 1:1000; loading ...; fig 1b
Voelkl J, Luong T, Tuffaha R, Musculus K, Auer T, Lian X, et al. SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling. J Clin Invest. 2018;128:3024-3040 pubmed publisher
  • western blot; human; loading ...; fig 8a
Schweitzer C, Zhang F, Boyer A, Valdez K, Cam M, Liang T. N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly. J Virol. 2018;92: pubmed publisher
  • western blot; human; loading ...; fig 2b
Sakre N, Wildey G, Behtaj M, Kresak A, Yang M, Fu P, et al. RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR. Oncotarget. 2017;8:5992-6002 pubmed publisher
  • western blot; human; 1:1000; fig 2
Cipriani G, Gibbons S, Verhulst P, Choi K, Eisenman S, Hein S, et al. Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol. 2016;2:40-47 pubmed
Chuang H, Tsai C, Hsueh C, Tan T. GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease. Sci Adv. 2018;4:eaat5401 pubmed publisher
product information
mab :
mab
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.