product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HES1 (D6P2U) Rabbit mAb
catalog :
11988S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/DilutionReference
  • immunocytochemistry; rat; 1:200; fig 1g
Del Debbio C, Mir Q, Parameswaran S, Mathews S, Xia X, Zheng L, et al. Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1. PLoS ONE. 2016;11:e0152025 pubmed publisher
  • western blot; rat; 1:1000; fig 6
  • immunohistochemistry; rat; 1:1000; fig 6
Zhang S, Wang P, Ren L, Hu C, Bi J. Protective effect of melatonin on soluble Aβ1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther. 2016;8:40 pubmed publisher
  • western blot; rat; fig 2
Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher
  • western blot; mouse; fig 6
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher
  • western blot; human; fig f4
Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
  • western blot; mouse; 1:3000; fig 6
Grimm P, Lazo-Fernandez Y, Delpire E, Wall S, Dorsey S, Weinman E, et al. Integrated compensatory network is activated in the absence of NCC phosphorylation. J Clin Invest. 2015;125:2136-50 pubmed publisher
Wang L, Song G, Liu M, Chen B, Chen Y, Shen Y, et al. MicroRNA-375 overexpression influences P19 cell proliferation, apoptosis and differentiation through the Notch signaling pathway. Int J Mol Med. 2016;37:47-55 pubmed publisher
Arruga F, Gizdić B, Serra S, Vaisitti T, Ciardullo C, Coscia M, et al. Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. Leukemia. 2014;28:1060-70 pubmed publisher
Yu M, Jiang M, Yang C, Wu Y, Liu Y, Cui Y, et al. Maternal high-fat diet affects Msi/Notch/Hes signaling in neural stem cells of offspring mice. J Nutr Biochem. 2014;25:227-31 pubmed publisher
product information
SKU :
11988S
Product-Name :
HES1 (D6P2U) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
30
Host :
Rabbit
Target :
HES1
Primary-Protein :
HES1
Alt-Names :
BHLHB39,Class B basic helix-loop-helix protein 39,FLJ20408,HES-1,HES1,HL,HRY,Hairy and enhancer of split 1,Hairy homolog,Hairy-like protein,Transcription factor HES-1,hHL,hairy and enhancer of split 1, (Drosophila)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.