| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; human; 1:200; loading ...
| Roy B, Ahmed I, Stubbs J, Zhang J, Attard T, Septer S, et al. DCLK1 isoforms and aberrant Notch signaling in the regulation of human and murine colitis. Cell Death Discov. 2021;7:169 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5c
| Roper N, Velez M, Chiappori A, Kim Y, Wei J, Sindiri S, et al. Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer. Nat Commun. 2021;12:3880 pubmed publisher |
- immunohistochemistry; mouse; 1:600; loading ...; fig 5d
| Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Ni W, Chen Z, Zhou X, Yang R, Yu M, Lu J, et al. Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma. Signal Transduct Target Ther. 2021;6:27 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 3d
- western blot; human; loading ...; fig 4a
| Liao T, Lin C, Jiang J, Yang S, Teng H, Yang M. Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer. Theranostics. 2020;10:6095-6112 pubmed publisher |
- western blot; human; 1:3000; loading ...
| Park D, Cheng J, McGrath J, Lim M, Cushman C, Swanson S, et al. Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. Nat Cell Biol. 2020;22:603-615 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7d
| Ocasio J, Babcock B, Malawsky D, Weir S, Loo L, Simon J, et al. scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy. Nat Commun. 2019;10:5829 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 5b
| Ouadah Y, Rojas E, Riordan D, Capostagno S, Kuo C, Krasnow M. Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. Cell. 2019;179:403-416.e23 pubmed publisher |
- immunohistochemistry; human; 1:6400; loading ...; fig 6e
| Haider S, Gamperl M, Burkard T, Kunihs V, Kaindl U, Junttila S, et al. Estrogen Signaling Drives Ciliogenesis in Human Endometrial Organoids. Endocrinology. 2019;160:2282-2297 pubmed publisher |
- western blot; human; loading ...; fig 3h
| Wang H, Xiang D, Liu B, He A, Randle H, Zhang K, et al. Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer. Cell. 2019;178:135-151.e19 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig ex10c
| Serra D, Mayr U, Boni A, Lukonin I, Rempfler M, Challet Meylan L, et al. Self-organization and symmetry breaking in intestinal organoid development. Nature. 2019;569:66-72 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; loading ...; fig 3e, 5b
| Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; fig 1c
- immunohistochemistry - paraffin section; mouse; 1:200; fig 1a
- western blot; mouse; fig s2f
| Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher |
- immunocytochemistry; rat; 1:100; loading ...; fig 5e
- immunohistochemistry; rat; 1:100; loading ...; fig 2e
- western blot; rat; 1:500; loading ...; fig 2a
| Zeng W, Han Y, Zhu G, Huang L, Deng Y, Wang Q, et al. Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia. BMC Neurosci. 2017;18:32 pubmed publisher |
- immunohistochemistry; rat; 1:1000; fig 6
- western blot; rat; 1:1000; fig 6
| Zhang S, Wang P, Ren L, Hu C, Bi J. Protective effect of melatonin on soluble A?1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther. 2016;8:40 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 6d
- western blot; human; 1:1000; loading ...; fig 2b
| Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7b
| Sellathurai J, Nielsen J, Hejbøl E, Jørgensen L, Dhawan J, Nielsen M, et al. Low Oxygen Tension Enhances Expression of Myogenic Genes When Human Myoblasts Are Activated from G0 Arrest. PLoS ONE. 2016;11:e0158860 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 3a
| Zeng J, Jing Y, Shi R, Pan X, Lai F, Liu W, et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. Cell Cycle. 2016;15:1602-10 pubmed publisher |
- immunocytochemistry; rat; 1:200; fig 1g
| Del Debbio C, Mir Q, Parameswaran S, Mathews S, Xia X, Zheng L, et al. Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1. PLoS ONE. 2016;11:e0152025 pubmed publisher |
| Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher |
- western blot; mouse; fig 6
| Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher |
- western blot; mouse; 1:3000; fig 6
| Grimm P, Lazo Fernández Y, Delpire E, Wall S, Dorsey S, Weinman E, et al. Integrated compensatory network is activated in the absence of NCC phosphorylation. J Clin Invest. 2015;125:2136-50 pubmed publisher |
- western blot; human; fig f4
| Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed |
- western blot; human; loading ...; fig 5c,6d
| Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed publisher |
| Ng S, Rideout W, Akama Garren E, Bhutkar A, Mercer K, Schenkel J, et al. CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer. Proc Natl Acad Sci U S A. 2019;: pubmed publisher |
| Parekh P, Garcia T, Waheeb R, Jain V, Gandhi P, Meistrich M, et al. Undifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation. FASEB J. 2019;:fj201802361R pubmed publisher |
| Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, et al. Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors. J Neurosci. 2019;39:2195-2207 pubmed publisher |
| Villar Prados A, Wu S, Court K, Ma S, LaFargue C, Chowdhury M, et al. Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4. Mol Cancer Ther. 2019;18:421-436 pubmed publisher |
| Liu Z, Zheng Z, Qi J, Wang J, Zhou Q, Hu F, et al. CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regeneration. J Biol Eng. 2018;12:35 pubmed publisher |
| Komori H, Golden K, Kobayashi T, Kageyama R, Lee C. Multilayered gene control drives timely exit from the stem cell state in uncommitted progenitors during Drosophila asymmetric neural stem cell division. Genes Dev. 2018;32:1550-1561 pubmed publisher |
| Azimi M, Le T, Brown N. Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018;102:40-52 pubmed publisher |
| Parry A, Hoare M, Bihary D, Hänsel Hertsch R, Smith S, Tomimatsu K, et al. NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence. Nat Commun. 2018;9:1840 pubmed publisher |
| Morgenstern Y, Das Adhikari U, Ayyash M, Elyada E, Tóth B, Moor A, et al. Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance. EMBO J. 2017;36:3046-3061 pubmed publisher |
| Long Q, Luo Q, Wang K, Bates A, Shetty A. Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells. Aging Dis. 2017;8:301-313 pubmed publisher |
| Taniguchi K, Moroishi T, de Jong P, Krawczyk M, Grebbin B, Luo H, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:1643-1648 pubmed publisher |
| Huang W, Martin E, Burman B, Gonzalez M, Kleer C. The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells. Oncotarget. 2016;7:25180-93 pubmed publisher |
| Wang L, Song G, Liu M, Chen B, Chen Y, Shen Y, et al. MicroRNA-375 overexpression influences P19 cell proliferation, apoptosis and differentiation through the Notch signaling pathway. Int J Mol Med. 2016;37:47-55 pubmed publisher |
| Vaughan A, Brumwell A, Xi Y, Gotts J, Brownfield D, Treutlein B, et al. Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury. Nature. 2015;517:621-5 pubmed publisher |
| Yu M, Jiang M, Yang C, Wu Y, Liu Y, Cui Y, et al. Maternal high-fat diet affects Msi/Notch/Hes signaling in neural stem cells of offspring mice. J Nutr Biochem. 2014;25:227-31 pubmed publisher |
| Arruga F, Gizdić B, Serra S, Vaisitti T, Ciardullo C, Coscia M, et al. Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. Leukemia. 2014;28:1060-70 pubmed publisher |
