product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CDK12 Antibody
catalog :
11973
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 1c
Yu F, Shi G, Cheng S, Chen J, Wu S, Wang Z, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Res. 2018;28:670-685 pubmed publisher
  • western blot; human; loading ...; fig 2a
Paculova H, Kramara J, Simečková S, Fedr R, Soucek K, Hylse O, et al. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumour Biol. 2017;39:1010428317727479 pubmed publisher
  • western blot; human
Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-1139 pubmed publisher
Schecher S, Walter B, Falkenstein M, Macher Goeppinger S, Stenzel P, Krümpelmann K, et al. Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer. Int J Cancer. 2017;141:1643-1653 pubmed publisher
product information
SKU :
11973S
Product-Name :
CDK12 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
205
Host :
Rabbit
Target :
CRK7
Primary-Protein :
CDK12
Alt-Names :
CDC2-related protein kinase 7,CDK12,CRK7,CRKR,CRKRS,Cdc2-related kinase, arginine/serine-rich,Cell division cycle 2-related protein kinase 7,Cell division protein kinase 12,KIAA0904,cyclin-dependent kinase 12
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.