product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TNF-α (D2D4) XP® Rabbit mAb (Rodent Specific)
catalog :
11948
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2D4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, flow cytometry
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4d
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Rajendran R, Rajendran V, Giraldo Velasquez M, Megalofonou F, Gurski F, Stadelmann C, et al. Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG35-55-Induced EAE. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5b
Takahashi K, Nakamura S, Otsu W, Shimazawa M, Hara H. Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation. J Neuroinflammation. 2021;18:164 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Tan S, Liu X, Chen L, Wu X, Tao L, Pan X, et al. Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis. Cell Death Dis. 2021;12:474 pubmed publisher
  • western blot; mouse; loading ...
Shin M, Vázquez Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón Pérez C, et al. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021;184:2715-2732.e23 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 9b
Kong Y, Xu S. Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation. Int J Mol Med. 2020;46:67-82 pubmed publisher
  • western blot; rat; loading ...; fig 1d
Himori K, Abe M, Tatebayashi D, Lee J, Westerblad H, Lanner J, et al. Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension. PLoS ONE. 2017;12:e0169146 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1h
Xiang N, Liu J, Liao Y, Huang Y, Wu Z, Bai Z, et al. Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway. Sci Rep. 2016;6:27583 pubmed publisher
  • western blot; rat; fig 7
Su R, Yan J, Yang H. Transgenerational Glucose Intolerance of Tumor Necrosis Factor with Epigenetic Alteration in Rat Perirenal Adipose Tissue Induced by Intrauterine Hyperglycemia. J Diabetes Res. 2016;2016:4952801 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5e
Srodulski S, Sharma S, Bachstetter A, Brelsfoard J, Pascual C, Xie X, et al. Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin. Mol Neurodegener. 2014;9:30 pubmed publisher
Hanhai Z, Bin Q, Shengjun Z, Jingbo L, Yinghan G, Lingxin C, et al. Neutrophil extracellular traps, released from neutrophil, promote microglia inflammation and contribute to poor outcome in subarachnoid hemorrhage. Aging (Albany NY). 2021;13:13108-13123 pubmed publisher
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed publisher
Xie W, Lu Q, Wang K, Lu J, Gu X, Zhu D, et al. miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin. J Cell Physiol. 2018;233:6615-6631 pubmed publisher
Pitman R, Wojdyla L, Puri N. Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma. Oncotarget. 2013;4:761-71 pubmed
Katayama M, Donai K, Sakakibara H, Ohtomo Y, Miyagawa M, Kuroda K, et al. Coffee consumption delays the hepatitis and suppresses the inflammation related gene expression in the Long-Evans Cinnamon rat. Clin Nutr. 2014;33:302-10 pubmed publisher
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, et al. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013;496:110-3 pubmed publisher
product information
SKU :
11948P
Product-Name :
TNF-α (D2D4) XP® Rabbit mAb (Rodent Specific)
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
M, R
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
17,25,28
Host :
Rabbit
Target :
TNF-alpha (mouse)
Primary-Protein :
TNF-a
Alt-Names :
Cachectin,DIF,MGC151434,TNF alpha,TNF-a,TNF-alpha,TNFalpha,Tnf,Tnfa,Tnfsf1a,Tnfsf2,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor necrosis factor, membrane form,Tumor necrosis factor, soluble form,tumor necrosis factor alpha,tumor necrosis factor-alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.