| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 2b
| Chen C, Zhang Z, Liu C, Wang B, Liu P, Fang S, et al. ATF4-dependent fructolysis fuels growth of glioblastoma multiforme. Nat Commun. 2022;13:6108 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s2b
- western blot; rat; 1:1000; loading ...; fig 2c, 2h
| Formigari G, D xe1 tilo M, Vareda B, Bonfante I, Cavaglieri C, Lopes de Faria J, et al. Renal protection induced by physical exercise may be mediated by the irisin/AMPK axis in diabetic nephropathy. Sci Rep. 2022;12:9062 pubmed publisher |
- western blot; human; loading ...; fig 1h
| Luo H, Song Y, Zhang J, Liu Y, Chen F, Wang Z, et al. MAT2A facilitates PDCD6 methylation and promotes cell growth under glucose deprivation in cervical cancer. Cell Death Discov. 2022;8:176 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6g
| Gyamfi J, Yeo J, Kwon D, Min B, Cha Y, Koo J, et al. Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer. NPJ Breast Cancer. 2021;7:129 pubmed publisher |
- western blot; rat; loading ...; fig 4c
| Li L, Li Q, Huang W, Han Y, Tan H, An M, et al. Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway. Front Pharmacol. 2021;12:589273 pubmed publisher |
- western blot; human; loading ...; fig s6a
| Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, et al. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021;296:100624 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1f
| Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S, Li X, et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol. 2021;4:61 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s3h
| Hermanova I, Z iga Garc a P, Caro Maldonado A, Fernandez Ruiz S, Salvador F, Mart n Mart n N, et al. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer. J Exp Med. 2020;217: pubmed publisher |
- western blot; human; loading ...; fig 1k
| Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, et al. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019;76:857-871.e9 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1s2c
| Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 3d
- western blot; mouse; loading ...; fig 2d
| Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 2b
- western blot; mouse; loading ...; fig 1a, 1b
- western blot; human; loading ...; fig 1a, 1b
| Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 3e
| Haikala H, Anttila J, Marques E, Raatikainen T, Ilander M, Hakanen H, et al. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy. Nat Commun. 2019;10:620 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 1f
| Li F, Liu J, Bao R, Yan G, Feng X, Xu Y, et al. Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nat Commun. 2018;9:508 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s3c
| Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 6b
- western blot; human; loading ...; fig 1f
| Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher |
- western blot; human; loading ...; fig 5m
| Gupta A, Anjomani Virmouni S, Koundouros N, Dimitriadi M, Choo Wing R, Valle A, et al. PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation. Mol Cell. 2017;65:999-1013.e7 pubmed publisher |
- western blot; mouse; fig s7d
| Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6c
| Hogarth M, Houweling P, Thomas K, Gordish Dressman H, Bello L, Pegoraro E, et al. Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. Nat Commun. 2017;8:14143 pubmed publisher |
- western blot; human; loading ...; fig s9d
| Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher |
- western blot; mouse; loading ...; fig 3g
| Liu Z, Gan L, Wu T, Feng F, Luo D, Gu H, et al. Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis. 2016;7:e2487 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5d
| Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, et al. Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med. 2016;8:1212-1228 pubmed publisher |
- western blot; human; loading ...; fig 2c, 5f, 5g
- western blot; rat; loading ...; fig 5h
| Yin C, He D, Chen S, Tan X, Sang N. Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget. 2016;7:47494-47510 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 10
| Sundararaman A, Amirtham U, Rangarajan A. Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation. J Biol Chem. 2016;291:14410-29 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1e
| Rao E, Zhang Y, Li Q, Hao J, Egilmez N, Suttles J, et al. AMPK-dependent and independent effects of AICAR and compound C on T-cell responses. Oncotarget. 2016;7:33783-95 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2b
| Camarda R, Zhou A, Kohnz R, Balakrishnan S, Mahieu C, Anderton B, et al. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016;22:427-32 pubmed publisher |
- flow cytometry; mouse; fig 7a
| Tellier J, Shi W, Minnich M, Liao Y, Crawford S, Smyth G, et al. Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response. Nat Immunol. 2016;17:323-30 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Douglas D, Pu C, Lewis J, Bhat R, Anwar Mohamed A, Logan M, et al. Oxidative Stress Attenuates Lipid Synthesis and Increases Mitochondrial Fatty Acid Oxidation in Hepatoma Cells Infected with Hepatitis C Virus. J Biol Chem. 2016;291:1974-90 pubmed publisher |
| Martin K, Celano S, Sheldon R, Jones R, Mackeigan J. Quantitative Analysis of Autophagy in Single Cells: Differential Response to Amino Acid and Glucose Starvation. bioRxiv. 2023;: pubmed publisher |
| Wu C, Dai C, Li X, Sun M, Chu H, Xuan Q, et al. AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy. Theranostics. 2022;12:7681-7698 pubmed publisher |
| Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch A, et al. Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Nat Commun. 2022;13:4327 pubmed publisher |
| Šimčíková D, Gardáš D, Hložková K, Hruda M, Zácek P, Rob L, et al. Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin. Cancer Metab. 2021;9:41 pubmed publisher |
| Lan F, Lin Y, Gao Z, Cacicedo J, Weikel K, Ido Y. Activation of LKB1 rescues 3T3-L1 adipocytes from senescence induced by Sirt1 knock-down: a pivotal role of LKB1 in cellular aging. Aging (Albany NY). 2020;12:18942-18956 pubmed publisher |
| Guieze R, Liu V, Rosebrock D, Jourdain A, Hernández Sánchez M, Martinez Zurita A, et al. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies. Cancer Cell. 2019;36:369-384.e13 pubmed publisher |
| Molusky M, Hsieh J, Lee S, Ramakrishnan R, Tascau L, Haeusler R, et al. Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic Consequences. Arterioscler Thromb Vasc Biol. 2018;38:1493-1503 pubmed publisher |
| Jiménez de Oya N, Blazquez A, Casas J, Saiz J, Martín Acebes M. Direct Activation of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by PF-06409577 Inhibits Flavivirus Infection through Modification of Host Cell Lipid Metabolism. Antimicrob Agents Chemother. 2018;62: pubmed publisher |
| Adams W, Chen Y, Kratchmarov R, Yen B, Nish S, Lin W, et al. Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Cell Rep. 2016;17:3142-3152 pubmed publisher |
