Cell Guidance Systems

protein

Recombinant HumanG-CSF, 2 μg

GFH72-2

GFH72-2

Recombinant HumanG-CSF, 2 μg

Growth Factors

Granulocyte-Colony Stimulating Factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilicGranulocyte proliferation, terminal differentiation, and activation.G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, Tumor Necrosis Factor α (TNF-α), Interleukin-1 (IL-1), or Interleukin-17 (IL-17). The functional activity ofG-CSF is mediated through theGranulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways.G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouseG-CSF proteins are cross-reactive.

Granulocyte Colony Stimulating Factor, granulocyte colony-stimulating factor, CSF-3, CSF3, MGI-1G, GM-CSF β, GM-CSFβ, pluripoietin, colony stimulating factor 3 (granulocyte), lenograstim, filgrastim, GCSF2, MGC45931, C17orf33, chromosome 17 open reading frame 33, CSF3OS, MGI-1G

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.