Cell Guidance Systems

protein

Recombinant Human Myostatin /GDF-8, 2 μg

GFH22-2

GFH22-2

Recombinant Human Myostatin /GDF-8, 2 μg

Growth Factors

Myostatin, also known asGDF-8, a conserved member of the TGF-β superfamily, is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscleGrowth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTRIIA, ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.

Fibroblast Growth Factor 8, FGF8, FGF 8, androgen-induced growth factor, AIGF, heparin-binding growth factor 8, HBGF-8

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.