Cell Guidance Systems

protein

Recombinant Human IL-17A/F, 5 μg

GFH161-5

GFH161-5

Recombinant Human IL-17A/F, 5 μg

Growth Factors

Interleukin-17A/F (IL-17A/F) is a heterodimer that is composed of the interleukin-17A (IL-17A) and interleukin-17F (IL-17F) members of the IL-17 family of cytokines. IL-17A/F is produced by T helper 17 cells (Th17) following interleukin-23 (IL-23) stimulation. IL-17A/F signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17A/F induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17A/F is less active than the IL-17A homodimer and showsGreater activity than the IL-17F homodimer. Human and rat IL-17A/F are active on mouse cells.

Interleukin-17A, interleukin 17A, IL17A, IL 17A

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.