Cell Guidance Systems

protein

Recombinant Human TNF-α, 10 μg

GFH111-10

GFH111-10

Recombinant Human TNF-α, 10 μg

Growth Factors

Tumor Necrosis Factor α (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and Natural Killer (NK) cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Tumor Necrosis Factor α, TNFa, TNFα, TNFSF2, cachectin, DIF, necrosin, cytotoxin, cachexin, TNF

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. Avoid freeze-thaw cycles