product summary
company name :
Cedarlanelabs
product type :
antibody
product name :
ANTI-MOUSE/HUMAN MAC-2 (GALECTIN-3), PURIFIED (CLONE M3/38) (RAT IGG2A)
catalog :
CL8942AP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M3/38
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry knockout validation
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:200; fig 5
Frunza O, Russo I, Saxena A, Shinde A, Humeres C, Hanif W, et al. Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis. Am J Pathol. 2016;186:1114-27 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4a, b, c
Manrique Acevedo C, Padilla J, Naz H, Woodford M, Ghiarone T, Aroor A, et al. Mineralocorticoid Receptor in Myeloid Cells Mediates Angiotensin II-Induced Vascular Dysfunction in Female Mice. Front Physiol. 2021;12:588358 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 4d
Zhan L, Fan L, Kodama L, Sohn P, Wong M, Mousa G, et al. A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1d, 2f
Asare Y, Koehncke J, Selle J, Simsekyilmaz S, Jankowski J, Shagdarsuren G, et al. Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice. Front Physiol. 2020;11:673 pubmed publisher
  • immunohistochemistry; mouse; 0.25 ug/ml; loading ...; fig 1c
Di Gregoli K, Somerville M, Bianco R, Thomas A, Frankow A, Newby A, et al. Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020;40:1491-1509 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5c
Thirugnanam K, Cossette S, Lu Q, Chowdhury S, Harmann L, Gupta A, et al. Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart. J Am Heart Assoc. 2019;8:e012792 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
Munro D, Wineberg Y, Tarnick J, Vink C, Li Z, Pridans C, et al. Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3C
Busnelli M, Manzini S, Hilvo M, Parolini C, Ganzetti G, Dellera F, et al. Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE-/- mice. Sci Rep. 2017;7:44503 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:50; loading ...; fig st10
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 1b
de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig s5d
Vermeij W, Dollé M, Reiling E, Jaarsma D, Payan Gomez C, Bombardieri C, et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice. Nature. 2016;537:427-431 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s5b
Cherepanova O, Gomez D, Shankman L, Swiatlowska P, Williams J, Sarmento O, et al. Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. Nat Med. 2016;22:657-65 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 1
Tan S, Krasnow M. Developmental origin of lung macrophage diversity. Development. 2016;143:1318-27 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
Dhondup Y, Sjaastad I, Scott H, Sandanger Ø, Zhang L, Haugstad S, et al. Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice. PLoS ONE. 2015;10:e0139715 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Spillane D, Wang D, Newbigging S, Wang Y, Shi C, Cho H, et al. Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms. PLoS ONE. 2015;10:e0135755 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4
Morley T, Xia J, Scherer P. Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nat Commun. 2015;6:7906 pubmed publisher
  • immunohistochemistry; mouse; fig 5b
ELDREDGE L, Treuting P, MANICONE A, Ziegler S, Parks W, McGuire J. CD11b(+) Mononuclear Cells Mitigate Hyperoxia-Induced Lung Injury in Neonatal Mice. Am J Respir Cell Mol Biol. 2016;54:273-83 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Sauter K, Pridans C, Sehgal A, Tsai Y, Bradford B, Raza S, et al. Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. J Leukoc Biol. 2014;96:265-74 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Kodama K, Horikoshi M, Toda K, Yamada S, Hara K, Irie J, et al. Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes. Proc Natl Acad Sci U S A. 2012;109:7049-54 pubmed publisher
Gras S, Blasco A, Mòdol Caballero G, Tarabal O, Casanovas A, Piedrafita L, et al. Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system. Aging (Albany NY). 2021;13:18051-18093 pubmed publisher
Simion V, Zhou H, Haemmig S, Pierce J, Mendes S, Tesmenitsky Y, et al. A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus. Nat Commun. 2020;11:6135 pubmed publisher
Melamed S, Avraham R, Rothbard D, Erez N, Israely T, Klausner Z, et al. Innate immune response in neuronopathic forms of Gaucher disease confers resistance against viral-induced encephalitis. Acta Neuropathol Commun. 2020;8:144 pubmed publisher
Kain D, Simon A, Greenberg A, Ben Zvi D, Gilburd B, Schneiderman J. Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction. PLoS ONE. 2018;13:e0203902 pubmed publisher
Jimenez V, Jambrina C, Casana E, Sacristan V, Munoz S, Darriba S, et al. FGF21 gene therapy as treatment for obesity and insulin resistance. EMBO Mol Med. 2018;10: pubmed publisher
Jauregui E, Mitchell D, Topping T, Hogarth C, Griswold M. Retinoic acid receptor signaling is necessary in steroidogenic cells for normal spermatogenesis and epididymal function. Development. 2018;145: pubmed publisher
Almabrouk T, White A, Ugusman A, Skiba D, Katwan O, Alganga H, et al. High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion. Front Physiol. 2018;9:51 pubmed publisher
Yu F, Dworski S, Medin J. Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency. Sci Rep. 2018;8:1808 pubmed publisher
Bornfeldt K, Kramer F, Batorsky A, Choi J, Hudkins K, Tontonoz P, et al. A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis. Am J Pathol. 2018;188:343-352 pubmed publisher
Lee J, Snyder E, Liu Y, Gu X, Wang J, Flowers B, et al. Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells. Nat Commun. 2017;8:14686 pubmed publisher
Park J, Kim M, Sun K, An Y, Gu X, Scherer P. VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements. Diabetes. 2017;66:1479-1490 pubmed publisher
Rowinska Z, Koeppel T, Sanati M, Schelzig H, Jankowski J, Weber C, et al. Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PLoS ONE. 2017;12:e0170644 pubmed publisher
Zhou Y, Chen H, Liu L, Yu X, Sukhova G, Yang M, et al. CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice. J Immunol. 2017;198:2568-2577 pubmed publisher
Adingupu D, Heinonen S, Andreasson A, Brusberg M, Ahnmark A, Behrendt M, et al. Hyperglycemia Induced by Glucokinase Deficiency Accelerates Atherosclerosis Development and Impairs Lesion Regression in Combined Heterozygous Glucokinase and the Apolipoprotein E-Knockout Mice. J Diabetes Res. 2016;2016:8630961 pubmed
Ringling R, Gastecki M, Woodford M, Lum Naihe K, Grant R, Pulakat L, et al. Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance. PLoS ONE. 2016;11:e0161939 pubmed publisher
Albanese I, Daskalopoulou S, Yu B, You Z, Genest J, Alsheikh Ali A, et al. The Urotensin II System and Carotid Atherosclerosis: A Role in Vascular Calcification. Front Pharmacol. 2016;7:149 pubmed publisher
White C, Jansen M, McGregor K, Mylonas K, Richardson R, Thomson A, et al. Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice. Endocrinology. 2016;157:346-57 pubmed publisher
Casellas A, Mallol C, Salavert A, Jimenez V, Garcia M, Agudo J, et al. Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage. J Biol Chem. 2015;290:16772-85 pubmed publisher
Medrikova D, Sijmonsma T, Sowodniok K, Richards D, Delacher M, Sticht C, et al. Brown adipose tissue harbors a distinct sub-population of regulatory T cells. PLoS ONE. 2015;10:e0118534 pubmed publisher
Everard A, Geurts L, Caesar R, Van Hul M, Matamoros S, Duparc T, et al. Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status. Nat Commun. 2014;5:5648 pubmed publisher
Finsen A, Ueland T, Sjaastad I, Ranheim T, Ahmed M, Dahl C, et al. The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling. PLoS ONE. 2014;9:e112172 pubmed publisher
Kodama K, Toda K, Morinaga S, Yamada S, Butte A. Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice. Diabetes. 2015;64:867-75 pubmed publisher
Ulleryd M, Bernberg E, Yang L, Bergström G, Johansson M. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783 pubmed publisher
Rowinska Z, Gorressen S, Merx M, Koeppel T, Liehn E, Zernecke A. Establishment of a new murine elastase-induced aneurysm model combined with transplantation. PLoS ONE. 2014;9:e102648 pubmed publisher
Luebben S, Kawabata T, Johnson C, O Sullivan M, Shima N. A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res. 2014;42:5605-15 pubmed publisher
Traber P, Zomer E. Therapy of experimental NASH and fibrosis with galectin inhibitors. PLoS ONE. 2013;8:e83481 pubmed publisher
Lindgren A, Levin M, Rodrigo Blomqvist S, Wikström J, Ahnmark A, Mogensen C, et al. Adiponectin receptor 2 deficiency results in reduced atherosclerosis in the brachiocephalic artery in apolipoprotein E deficient mice. PLoS ONE. 2013;8:e80330 pubmed publisher
Tan X, Carretero J, Chen Z, Zhang J, Wang Y, Chen J, et al. Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer. PLoS ONE. 2013;8:e80885 pubmed publisher
Seamons A, Treuting P, Brabb T, Maggio Price L. Characterization of dextran sodium sulfate-induced inflammation and colonic tumorigenesis in Smad3(-/-) mice with dysregulated TGF?. PLoS ONE. 2013;8:e79182 pubmed publisher
Ji K, Akgul G, Wollmuth L, Tsirka S. Microglia actively regulate the number of functional synapses. PLoS ONE. 2013;8:e56293 pubmed publisher
Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, et al. CD98hc (SLC3A2) regulation of skin homeostasis wanes with age. J Exp Med. 2013;210:173-90 pubmed publisher
RAMOS H, Lanteri M, Blahnik G, Negash A, Suthar M, Brassil M, et al. IL-1? signaling promotes CNS-intrinsic immune control of West Nile virus infection. PLoS Pathog. 2012;8:e1003039 pubmed publisher
Ji K, Tsirka S. Inflammation modulates expression of laminin in the central nervous system following ischemic injury. J Neuroinflammation. 2012;9:159 pubmed publisher
Lutz S, Hennige A, Feil S, Peter A, Gerling A, Machann J, et al. Genetic ablation of cGMP-dependent protein kinase type I causes liver inflammation and fasting hyperglycemia. Diabetes. 2011;60:1566-76 pubmed publisher
Perfield J, Lee Y, Shulman G, Samuel V, Jurczak M, Chang E, et al. Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance. Diabetes. 2011;60:1168-76 pubmed publisher
Filippov S, Koenig G, Chun T, Hotary K, Ota I, Bugge T, et al. MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells. J Exp Med. 2005;202:663-71 pubmed
company information
Cedarlanelabs
4410 Paletta Court Burlington, Ontario, L7L 5R2
service@cedarlanelabs.com
http://www.cedarlanelabs.com
headquarters: Canada