product summary
company name :
Cayman Chemical
product type :
antibody
product name :
COX-2 Monoclonal Antibody (Clone CX229)
catalog :
160112
clonality :
monoclonal
conjugate :
nonconjugated
clone name :
CX229
reactivity :
human, rat, dogs
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 2a
Sundar I, Javed F, Romanos G, Rahman I. E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts. Oncotarget. 2016;7:77196-77204 pubmed publisher
  • immunohistochemistry; human; 1:400; fig 4
Flanagan L, Meyer M, Fay J, Curry S, Bacon O, Duessmann H, et al. Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach. Cell Death Dis. 2016;7:e2087 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:800; fig 4
Willems N, Tellegen A, Bergknut N, Creemers L, Wolfswinkel J, Freudigmann C, et al. Inflammatory profiles in canine intervertebral disc degeneration. BMC Vet Res. 2016;12:10 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2b
  • western blot; human; 1:1000; fig 2d
Nagaraja A, Dorniak P, Sadaoui N, Kang Y, Lin T, Armaiz Pena G, et al. Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene. 2016;35:2390-7 pubmed publisher
  • western blot; rat; 1:1000; fig 6
Liu K, Chuang S, Long C, Lee Y, Wang C, Lu M, et al. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Am J Physiol Renal Physiol. 2015;309:F318-31 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:50; tbl s4
Larsson K, Kock A, Idborg H, Arsenian Henriksson M, Martinsson T, Johnsen J, et al. COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset. Proc Natl Acad Sci U S A. 2015;112:8070-5 pubmed publisher
  • immunohistochemistry; human
Urban J, Kuźbicki Å, Szatkowski G, Stanek Widera A, Lange D, Chwirot B. Stromal, rather than epithelial cyclooxygenase-2 (COX-2) expression is associated with overall survival of breast cancer patients. BMC Cancer. 2014;14:732 pubmed publisher
Bronger H, Singer J, Windmüller C, Reuning U, Zech D, Delbridge C, et al. CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer. Br J Cancer. 2016;115:553-63 pubmed publisher
van Roosmalen I, Reis C, Setroikromo R, Yuvaraj S, Joseph J, Tepper P, et al. The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma. Springerplus. 2014;3:495 pubmed publisher
Bermudez Y, Stratton S, Curiel Lewandrowski C, Warneke J, Hu C, BOWDEN G, et al. Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin. Cancer Prev Res (Phila). 2015;8:720-8 pubmed publisher
Chua C, Liu Y, Granberg K, Hu L, Haapasalo H, Annala M, et al. IGFBP2 potentiates nuclear EGFR-STAT3 signaling. Oncogene. 2016;35:738-47 pubmed publisher
Tsai C, Yang C, Wang J, Tsai Y, Tseng L, King K, et al. Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells. Evid Based Complement Alternat Med. 2013;2013:421051 pubmed publisher
Lloyd J, Masko E, Wu C, Keenan M, Pilla D, Aronson W, et al. Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. Prostate Cancer Prostatic Dis. 2013;16:285-91 pubmed publisher
Wang X, Zhang L, O NEILL A, Bahamon B, Alsop D, Mier J, et al. Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts. Br J Cancer. 2013;108:319-26 pubmed publisher
Prins M, Verhage R, ten Kate F, van Hillegersberg R. Cyclooxygenase isoenzyme-2 and vascular endothelial growth factor are associated with poor prognosis in esophageal adenocarcinoma. J Gastrointest Surg. 2012;16:956-66 pubmed publisher
Tuynman J, Lagarde S, ten Kate F, Richel D, van Lanschot J. Met expression is an independent prognostic risk factor in patients with oesophageal adenocarcinoma. Br J Cancer. 2008;98:1102-8 pubmed publisher
Mounier C, Wendum D, Greenspan E, Flejou J, Rosenberg D, Lambeau G. Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate. Br J Cancer. 2008;98:587-95 pubmed publisher
Rask K, Zhu Y, Wang W, Hedin L, Sundfeldt K. Ovarian epithelial cancer: a role for PGE2-synthesis and signalling in malignant transformation and progression. Mol Cancer. 2006;5:62 pubmed
Joo Y, Chung I, Park Y, Koh Y, Lee J, Park C, et al. Expression of cyclooxygenase-2, p53 and Ki-67 in gastric cancer. J Korean Med Sci. 2006;21:871-6 pubmed
Boland G, Butt I, Prasad R, Knox W, Bundred N. COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ. Br J Cancer. 2004;90:423-9 pubmed
company information
Cayman Chemical
180 East Ellsworth Road Ann Arbor, Michigan 48108
custserv@caymanchem.com
http://www.caymanchem.com
headquarters: USA