product summary
company name :
Cayman Chemical
product type :
antibody
product name :
HIF-1 (C-Term) Polyclonal Antibody
catalog :
10006421
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig s2a
  • western blot; mouse; fig s2n
Longchamp A, Mirabella T, Arduini A, MacArthur M, Das A, Treviño Villarreal J, et al. Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production. Cell. 2018;173:117-129.e14 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 1b
Sala M, Chen C, Zhang Q, Do Umehara H, Wu W, Misharin A, et al. JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension. J Biol Chem. 2018;293:271-284 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1c
Bäcker V, Cheung F, Siveke J, Fandrey J, Winning S. Knockdown of myeloid cell hypoxia-inducible factor-1? ameliorates the acute pathology in DSS-induced colitis. PLoS ONE. 2017;12:e0190074 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 2a
Lajko M, Cardona H, Taylor J, Shah R, Farrow K, Fawzi A. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS ONE. 2016;11:e0166886 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig s2a
Thienpont B, Steinbacher J, Zhao H, D Anna F, Kuchnio A, Ploumakis A, et al. Tumour hypoxia causes DNA hypermethylation by reducing TET activity. Nature. 2016;537:63-68 pubmed publisher
  • chromatin immunoprecipitation; human; fig 4c
  • western blot; human; fig 4a
Ramakrishnan S, Ku S, Ciamporcero E, Miles K, Attwood K, Chintala S, et al. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma. BMC Cancer. 2016;16:617 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:10,000; loading ...; fig s4d
  • western blot; mouse; loading ...; fig s4i
Kobayashi H, Liu Q, Binns T, Urrutia A, Davidoff O, Kapitsinou P, et al. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest. 2016;126:1926-38 pubmed publisher
  • western blot; mouse; 1:1000; fig 4f
Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed publisher
Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, et al. BCAT1 restricts ?KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation. Nature. 2017;551:384-388 pubmed publisher
Kathiriya J, Nakra N, Nixon J, Patel P, Vaghasiya V, Alhassani A, et al. Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis. Cell Death Discov. 2017;3:17010 pubmed publisher
Farsijani N, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, et al. Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest. 2016;126:1425-37 pubmed publisher
Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, et al. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nat Immunol. 2016;17:277-85 pubmed publisher
company information
Cayman Chemical
180 East Ellsworth Road Ann Arbor, Michigan 48108
custserv@caymanchem.com
http://www.caymanchem.com
headquarters: USA