| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:4000; fig 5
- immunocytochemistry; human; 1:500; fig s5
- western blot knockout validation; mouse; 1:5000; fig 5
| Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- immunocytochemistry; mouse; fig 1
- western blot; mouse; fig 1
| Shen W, Li H, Chen G, Chern Y, Tu P. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Autophagy. 2015;11:685-700 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200
- immunocytochemistry; human; 1:40
| Nakamura M, Murray M, Lin W, Kusaka H, Dickson D. Optineurin immunoreactivity in neuronal and glial intranuclear inclusions in adult-onset neuronal intranuclear inclusion disease. Am J Neurodegener Dis. 2014;3:93-102 pubmed |
| Zhang R, Varela M, Vallentgoed W, Forn Cuni G, van der Vaart M, Meijer A. The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. 2019;15:e1007329 pubmed publisher |
| Ying H, Turturro S, Nguyen T, Shen X, Zelkha R, Johnson E, et al. Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene. BMC Cell Biol. 2015;16:14 pubmed publisher |
| Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, et al. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant. Acta Neuropathol Commun. 2014;2:172 pubmed publisher |
| Paulus J, Link B. Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics. PLoS ONE. 2014;9:e109922 pubmed publisher |
| Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed publisher |
| Deng H, Chen W, Hong S, Boycott K, Gorrie G, Siddique N, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 2011;477:211-5 pubmed publisher |
