| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry knockout validation; mouse; 1:100; fig 5
| Kwak M, Johnson D, Zhu C, Lee S, Ye D, Luong R, et al. Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors. PLoS ONE. 2013;8:e53476 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:250; fig 4e
- immunoprecipitation; mouse; loading ...; fig 1c
- immunocytochemistry; mouse; 1:100; loading ...; fig 2f
- western blot; mouse; loading ...; fig 1c
| Lee Y, Chen M, Lee J, Zhang J, Lin S, Fu T, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science. 2019;364: pubmed publisher |
- western blot; human; loading ...; fig 1b
| Kimura M, Hashimoto N, Kusunose M, Aoyama D, Sakamoto K, Miyazaki S, et al. Exogenous induction of unphosphorylated PTEN reduces TGFβ-induced extracellular matrix expressions in lung fibroblasts. Wound Repair Regen. 2017;25:86-97 pubmed publisher |
- western blot; human; loading ...; fig 2C
| Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher |
- immunocytochemistry; mouse; 1:25; fig 3
| van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher |
- immunohistochemistry - paraffin section; human; tbl 1
- western blot; human; fig 1
| Castillo Martin M, Thin T, Collazo Lorduy A, Cordon Cardo C. Immunopathologic Assessment of PTEN Expression. Methods Mol Biol. 2016;1388:23-37 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 2a
| Castillo Martin M, Collazo Lorduy A, Gladoun N, Hyun G, Cordon Cardo C. H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases. J Pediatr Urol. 2016;12:91.e1-7 pubmed publisher |
- western blot; human; fig 1
| Ho J, Bassi C, Stambolic V. Characterization of nuclear PTEN and its post translational modifications. Methods. 2015;77-78:104-11 pubmed publisher |
- immunohistochemistry; human; tbl 2
| Eritja N, Santacana M, Maiques O, González Tallada X, Dolcet X, Matias Guiu X. Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model. Methods. 2015;77-78:31-40 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50; fig 1
| Gallardo A, Lerma E, Escuin D, Tibau A, Munoz J, Ojeda B, et al. Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas. Br J Cancer. 2012;106:1367-73 pubmed publisher |
| Wozniak D, Kajdacsy Balla A, Macias V, Ball Kell S, Zenner M, Bie W, et al. PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. Nat Commun. 2017;8:1508 pubmed publisher |
| Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher |
| Carico C, Nuno M, Mukherjee D, Elramsisy A, Dantis J, Hu J, et al. Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era. PLoS ONE. 2012;7:e33684 pubmed publisher |
| Kim J, Bonifant C, Bunz F, Lane W, Waldman T. Epitope tagging of endogenous genes in diverse human cell lines. Nucleic Acids Res. 2008;36:e127 pubmed publisher |
| Cloughesy T, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, et al. Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008;5:e8 pubmed publisher |
