Anti-human CD86 APC | Caprico Biotechnologies 105745 product information

product summary

company name :

Caprico Biotechnologies

product type :

antibody

product name :

Anti-human CD86 APC

catalog :

105745

quantity :

100 Tests

price :

240.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

BU63

reactivity :

human

application :

flow cytometry

more info or order :

Caprico Biotechnologies product webpage

product information

Catalog Number :

105745

Product Name :

Anti-human CD86 APC

Product Type :

Flow cytometry primary antibody

Host Species :

Mouse

Clonality :

monoclonal

Conjugation :

APC

Clone Name :

BU63

Isotype :

IgG1,k

Size :

100 Tests

List Price :

240.00 USD

Product Description :

BU63 recognizes ~70Kda a surface antigen protein of Ig superfamily characterized as CD86 expressed by most antigen presenting cells (APC). Depending on the immunological condition, CD86 specifically binds with its two ligands CD28 and CD152 (CTLA-4) expressed by T cells. Binding with CD28, CD86 provides stimulatory signal and activates T cells whereas binding with CD152 (CTLA-4) CD86 provides inhibitory signal to T cells. Generally, high-level CD86 expression was noticed on peripheral monocytes, tissue macrophages and dendritic cells, and also on activated B cells. CD86 is useful in the clinical diagnosis of cancer cells including malignant Hodgkin’s and non-hodgkin’s diseases

Immunogen :

B-lymphoblastoid cell line ARH 77

Buffer :

PBS pH 7.2, 0.2% BSA (w/v), 0.09% sodium azide

Concentration :

50 ug/mL

Uses :

Flow Cytometry

Application Summary :

flow

Storage :

more info or order :

Caprico Biotechnologies product webpage