Anti-p53 Purified (PAb-122) | Caprico Biotechnologies 102101 product information

product summary

company name :

Caprico Biotechnologies

product type :

antibody

product name :

Anti-p53 Purified (PAb-122)

catalog :

102101

quantity :

100µg

price :

195.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAb-122

reactivity :

human

application :

flow cytometry

more info or order :

Caprico Biotechnologies product webpage

product information

Catalog Number :

102101

Product Name :

Anti-p53 Purified (PAb-122)

Product Type :

Flow cytometry primary antibody

Host Species :

Mouse

Clonality :

monoclonal

Clone Name :

PAb-122

Isotype :

IgG2b,k

Size :

100µg

List Price :

195.00 USD

Product Description :

p53, a DNA-binding, oligomerization domain- and transcription activation domaincontaining tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.

Immunogen :

SV40-transformed, 3T3 clone 4 mouse cells

Buffer :

PBS pH 7.2, 0.09% sodium azide

Concentration :

0.5mg/mL

Uses :

Western Blot

Application Summary :

flow

Storage :

4°C

more info or order :

Caprico Biotechnologies product webpage