protein

Recombinant Human IFN gamma Protein

R00393

100µg/vial

Recombinant Human IFN gamma Protein

https://www.bosterbio.comrecombinant-human-ifn-gamma-protein-r00393-boster.html

IFNG

100µg/vial

Human

Interferon gamma (IFN ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulatedwith phytohemagglutinin, and by others as a productofantigen-stimulatedlymphocytes ortuberculin-sensitized mouseperitoneal lymphocytes challenged with PPD.The resulting supernatants were shown toinhibit growth of vesicular stomatitisvirus. IFN is a cytokine that is critical for innate and adaptive immunityagainst viral, some bacterial and protozoal infections. IFN is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. The importance of IFN in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatoryand immunomodulatoryeffects. IFN is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.

E. coli Gln24-Gly161

Lyophilized

Reconstitute in ddH2O at 100 μg/mL.

>95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.

Lyophilized recombinant human Interferon gamma remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIFNγremains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

P01579

16.1KD