TPSAB1 Tryptase Alpha/Beta 1 Human Recombinant Protein | Boster PROTQ15661 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

TPSAB1 Tryptase Alpha/Beta 1 Human Recombinant Protein

catalog :

PROTQ15661

quantity :

2 ug, 10 ug, 1 mg

product information

sku :

PROTQ15661

status :

Enabled

name :

TPSAB1 Tryptase Alpha/Beta 1 Human Recombinant Protein

gene name :

TPSAB1

price various sizes :

Sample: 2ug / $153 Regular: 10ug / $230 Bulk: 1mg / $4663

conjugate :

contents :

The TPSAB1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

description :

TPSAB1 Human Recombinant produced in E. coli is a single polypeptide chain containing 270 amino acids (31-275) and having a molecular mass of 30.1 kDa. TPSAB1 is fused to a 25 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

short description :

TPSAB30.1 kDa. TPSAB1 is fused to a 25 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

description1 :

Introduction . Tryptase alpha/beta-1 (TPSAB1) is a tryptase which is the key neutral protease present in mast cells and is discharged upon the coupled activation-degranulation response of this cell type. TPSAB1 is enzymatically active only as a heparin-stabilized tetramer, and is resistant to all known endogenous proteinase inhibitors. TPSAB1 is implicated as a mediator in the pathogenesis of asthma and other allergic and inflammatory disorders.

description2 :

Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHMIVGGQ EAPRSKWPWQ VSLRVHGPYW MHFCGGSLIH PQWVLTAAHC VGPDVKDLAA LRVQLREQHL YYQDQLLPVS RIIVHPQFYT AQIGADIALL ELEEPVNVSS HVHTVTLPPA SETFPPGMPC WVTGWGDVDN DERLPPPFPL KQVKVPIMEN HICDAKYHLG AYTGDDVRIV RDDMLCAGNT RRDSCQGDSG GPLVCKVNGT WLQAGVVSWG EGCAQPNRPG IYTRVTYYLD WIHHYVPKKP.

size :

2 ug, 10 ug, 1 mg

uniprot id :

Q15661

host :

form :

Sterile Filtered colorless solution.

purification :

Greater than 85% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Tryptase alpha/beta-1;Tryptase-1;3.4.21.59;Tryptase I;Tryptase alpha-1;TPSAB1;TPS1, TPS2, TPSB1;

gene full name :

Tryptase alpha/beta-1

protein function :

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

subcellular localization :

Secreted. Released from the secretory granules upon mast cell activation.

tissue specificity :

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level).

source :

E.coli

last modified :

4/18/19 6:56