TPSAB1 Human, Tryptase Alpha/Beta 1 Human Recombinant Protein, Sf9

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product summary

company name :

Boster

product type :

protein

product name :

TPSAB1 Human, Tryptase Alpha/Beta 1 Human Recombinant Protein, Sf9

catalog :

PROTQ15661-1

quantity :

2 ug , 10 ug , 1 mg

product information

sku :

PROTQ15661-1

status :

Enabled

name :

TPSAB1 Human, Tryptase Alpha/Beta 1 Human Recombinant Protein, Sf9

gene name :

TPSAB1

price various sizes :

Sample: 2ug / $151.7 Regular: 10ug / $230 Bulk: 1mg / $4661.7

conjugate :

contents :

TPSAB1 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) 20% glycerol.

description :

TPSAB1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (31-275 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 251 amino acids and having a molecular mass of 28.2kDa.TPSAB1 shows multiple bands between 28-40kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

short description :

TPSAB2528.2kDa.TPSAB1 shows multiple bands between 28-40kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

description1 :

Introduction . Tryptase alpha/beta-1 (TPSAB1) is a tryptase which is the key neutral protease present in mast cells and is discharged upon the coupled activation-degranulation response of this cell type. TPSAB1 is enzymatically active only as a heparin-stabilized tetramer, and is resistant to all known endogenous proteinase inhibitors. TPSAB1 is implicated as a mediator in the pathogenesis of asthma and other allergic and inflammatory disorders.

description2 :

Amino Acid Sequence IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKPHHHHH H.

size :

2 ug , 10 ug , 1 mg

uniprot id :

Q15661

host :

form :

Sterile Filtered colorless solution.

purification :

Greater than 90.0% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Tryptase alpha/beta-1;Tryptase-1;3.4.21.59;Tryptase I;Tryptase alpha-1;TPSAB1;TPS1, TPS2, TPSB1;

gene full name :

Tryptase alpha/beta-1

protein function :

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

subcellular localization :

Secreted. Released from the secretory granules upon mast cell activation.

tissue specificity :

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level).

source :

Sf9,Baculovirus cells.

last modified :

4/18/19 6:56