GH Growth Hormone Ovine Recombinant Protein | Boster PROTP67930 product information

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product summary

company name :

Boster

product type :

protein

product name :

GH Growth Hormone Ovine Recombinant Protein

catalog :

PROTP67930

quantity :

20 ug, 100 ug, 1 mg

product information

SKU :

PROTP67930

Product Name :

GH Growth Hormone Ovine Recombinant Protein

Product Page URL :

https://www.bosterbio.comgh-growth-hormone-ovine-recombinant-protein-protp67930-boster.html

Gene Name :

GH1

Size :

20 ug, 100 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Description :

Growth Hormone Ovine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 22015 Dalton. The GH Ovine Recombinant is purified by proprietary chromatographic techniques.

Source :

E. Coli

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.

AA Sequence and/or Biological Activity :

Amino Acid Sequence:1 afpamslsgl fanavlraqh lhqlaadtfk efertyipeg qrysiqntqv51 afcfsetipa ptgkneaqqk sdlellrisl lliqswlgpl qflsrvftns101 lvfgtsdrvy eklkdleegi lalmreledv tpragqilkq tydkfdtnmr151 sddallknyg llscfrkdlh ktetylrvmk crrfgeasca fBiological Activity: The activity as determined by the dose-dependant stimulation of the proliferation FDCP13B9 cells.

Purification :

Greater than 98.0% as determined by:. (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

Storage :

Lyophilized Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GH Ovine should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P67930

Gene Full Name :

Somatotropin

Synonyms :

Somatotropin;Growth hormone;GH1;

Protein Function :

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Subcellular Localization :

Secreted.