YBX1 Recombinant Protein Human Y Box Binding Protein 1 | Boster PROTP67809 product information

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product summary

company name :

Boster

product type :

protein

product name :

YBX1 Recombinant Protein Human Y Box Binding Protein 1

catalog :

PROTP67809

quantity :

5 ug, 20 ug, 1 mg

product information

sku :

PROTP67809

status :

Enabled

name :

YBX1 Recombinant Protein Human Y Box Binding Protein 1

gene name :

YBX1

price various sizes :

Sample: 5ug / $153 Regular: 20ug / $230 Bulk: 1mg / $2483

conjugate :

contents :

YBX1 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH7.4) and 20% glycerol.

description :

YBX1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 347 amino acids (1-324a.a) and having a molecular mass of 38.3kDa (molecular size on SDS-PAGE will appear higher). YBX1 is fused to a 23 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

short description :

YBX38.3kDa (molecular size on SDS-PAGE will appear higher). YBX1 is fused to a 23 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

description1 :

Introduction . Y Box Binding Protein 1 (YBX1) is a part of the CRD-mediated complex which promotes MYC mRNA stability. YBX1 takes part in mammalian selenoprotein translation and mediates pre-mRNA alternative splicing regulation. YBX1 uses as a drug target in cancer therapy due to its ability to replicate adenovirus type 5, a commonly used vector in gene therapy.

description2 :

Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMSSEAET QQPPAAPPAA PALSAADTKP GTTGSGAGSG GPGGLTSAAP AGGDKKVIAT KVLGTVKWFN VRNGYGFINR NDTKEDVFVH QTAIKKNNPR KYLRSVGDGE TVEFDVVEGE KGAEAANVTG PGGVPVQGSK YAADRNHYRR YPRRRGPPRN YQQNYQNSES GEKNEGSESA PEGQAQQRRP YRRRRFPPYY MRRPYGRRPQ YSNPPVQGEV MEGADNQGAG EQGRPVRQNM YRGYRPRFRR GPPRQRQPRE DGNEEDKENQ GDETQGQQPP QRRYRRNFNY RRRRPENPKP QDGKETKAAD PPAENSSAPE AEQGGAE.

size :

5 ug, 20 ug, 1 mg

uniprot id :

P67809

host :

form :

Sterile Filtered clear solution.

purification :

Greater than 85.0% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Nuclease-sensitive element-binding protein 1;CCAAT-binding transcription factor I subunit A;CBF-A;DNA-binding protein B;DBPB;Enhancer factor I subunit A;EFI-A;Y-box transcription factor;Y-box-binding protein 1;YB-1;YBX1;NSEP1, YB1;

gene full name :

Nuclease-sensitive element-binding protein 1

protein function :

Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro.

subcellular localization :

Cytoplasm. Nucleus. Cytoplasmic granule

source :

E. Coli

last modified :

4/18/19 6:56