GABARAPL2 GABA(A) Receptor-Associated Protein Like 2 Human Recombinant Protein

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

GABARAPL2 GABA(A) Receptor-Associated Protein Like 2 Human Recombinant Protein

catalog :

PROTP60520

quantity :

2 ug, 10 ug, 1 mg

product information

sku :

PROTP60520

status :

Enabled

name :

GABARAPL2 GABA(A) Receptor-Associated Protein Like 2 Human Recombinant Protein

gene name :

GABARAPL2

price various sizes :

Sample: 2ug / $153 Regular: 10ug / $230 Bulk: 1mg / $4663

conjugate :

contents :

The GABARAPL2 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 5mM DTT and 20% glycerol.

description :

GABARAPL2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 137 amino acids (1-117a.a.) and having a molecular mass of 15.8kDa. GABARAPL2 is fused to a 20 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

short description :

description1 :

Introduction . GABARAPL2 takes part in intra Golgi traffic and modulates intra Golgi transport by coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.

description2 :

Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF

size :

2 ug, 10 ug, 1 mg

uniprot id :

P60520

host :

form :

Sterile Filtered clear solution.

purification :

Greater than 90% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Gamma-aminobutyric acid receptor-associated protein-like 2;GABA(A) receptor-associated protein-like 2;Ganglioside expression factor 2;GEF-2;General protein transport factor p16;Golgi-associated ATPase enhancer of 16 kDa;GATE-16;MAP1 light chain 3-related protein;GABARAPL2;FLC3A, GEF2;

gene full name :

Gamma-aminobutyric acid receptor-associated protein-like 2

protein function :

Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

subcellular localization :

Golgi apparatus

tissue specificity :

Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.

source :

E. Coli

last modified :

4/18/19 6:56