CRISP3 Cysteine-Rich Secretory Protein 3 Human Recombinant Protein

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product summary

company name :

Boster

product type :

protein

product name :

CRISP3 Cysteine-Rich Secretory Protein 3 Human Recombinant Protein

catalog :

PROTP54108

quantity :

2 ug, 10 ug, 1 mg

product information

SKU :

PROTP54108

Product Name :

CRISP3 Cysteine-Rich Secretory Protein 3 Human Recombinant Protein

Product Page URL :

https://www.bosterbio.comcrisp3-cysteine-rich-secretory-protein-3-human-recombinant-protein-protp54108-boster.html

Gene Name :

CRISP3

Size :

2 ug, 10 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: Cysteine-rich secretory protein 3 (CRISP3) is a member of the CRISP family of proteins having a pathogenesis related protein 1 (PR1) domain at its N-terminal and ion channel regulatory (ICR) domain at its C-terminal linked by a hinge region. CRISP3 transcripts are present predominantly in the prostate. CRISP3 expression is low in benign prostatic epithelium but is highly upregulated in the majority of high-grade prostatic intraepithelial neoplasia lesions and in most primary prostate tumors and metastases. CRISP3 is one of the genes which are most often upregulated in prostate cancer. Human Prostate Secretory Protein (PSP94 binds human CRISP3 with a very high affinity.

Description :

CRISP3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (21-245) containing 235 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 26.74kDa.

Source :

E. Coli

Form :

Filtered colorless solution.

AA Sequence and/or Biological Activity :

Amino Acid Sequence:MKHHHHHHASNEDKDPAFTA LLTTQTQVQR EIVNKHNELR RAVSPPARNM LKMEWNKEAA ANAQKWANQC NYRHSNPKDR MTSLKCGENL YMSSASSSWS QAIQSWFDEY NDFDFGVGPK TPNAVVGHYT QVVWYSSYLV GCGNAYCPNQ KVLKYYYVCQ YCPAGNWANR LYVPYEQGAP CASCPDNCDD GLCTNGCKYE DLYSNCKSLK LTLTCKHQLV RDSCKASCNC SNSIY.

Purification :

Greater than 85.0% as determined by SDS-PAGE.

Storage :

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Uniprot ID :

P54108

Gene Full Name :

Cysteine-rich secretory protein 3

Synonyms :

Cysteine-rich secretory protein 3;CRISP-3;Specific granule protein of 28 kDa;SGP28;CRISP3;

Subcellular Localization :

Secreted. In neutrophils, localized in specific granules.

Tissue Specificity :

Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon.