GM-CSF Granulocyte Macrophage-Colony Stimulating Factor Rat Recombinant Protein

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product summary

company name :

Boster

product type :

protein

product name :

GM-CSF Granulocyte Macrophage-Colony Stimulating Factor Rat Recombinant Protein

catalog :

PROTP48750

quantity :

5 ug, 20 ug, 1 mg

product information

SKU :

PROTP48750

Product Name :

GM-CSF Granulocyte Macrophage-Colony Stimulating Factor Rat Recombinant Protein

Product Page URL :

https://www.bosterbio.comgm-csf-granulocyte-macrophage-colony-stimulating-factor-rat-recombinant-protein-protp48750-boster.html

Gene Name :

Csf2

Size :

5 ug, 20 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Description :

Granulocyte Macrophage Colony Stimulating Factor Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 128 amino acids and having a molecular mass of 14590.65 Dalton. GM-CSF Rat Recombinant is purified by proprietary chromatographic techniques.

Source :

E. Coli

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

GM-CSF Rat was lyophilized with no additives.

AA Sequence and/or Biological Activity :

Amino Acid Sequence:MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSIQRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIEVTTFEDFIKN LKGFLFDIPF DCWKPVQK. Biological Activity: The ED50 range = 0.001-0.01ng/ml corresponding to a specific activity of 100,000,000-1,000,000,000IU/mg, determined by the dose dependent proliferation of murine MC/9 cells.

Purification :

Greater than 95.0% as determined by:. (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.

Storage :

Lyophilized Granulocyte Macrophage Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GMCSF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P48750

Gene Full Name :

Granulocyte-macrophage colony-stimulating factor

Synonyms :

Granulocyte-macrophage colony-stimulating factor;GM-CSF;Colony-stimulating factor;CSF;Csf2;Csfgm;

Protein Function :

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Subcellular Localization :

Secreted.