IL-13 Interleukin-13 109 a.a. Rat Recombinant Protein | Boster PROTP42203 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

IL-13 Interleukin-13 109 a.a. Rat Recombinant Protein

catalog :

PROTP42203

quantity :

2 ug, 10 ug, 1 mg

product information

SKU :

PROTP42203

Product Name :

IL-13 Interleukin-13 109 a.a. Rat Recombinant Protein

Product Page URL :

https://www.bosterbio.comil-13-interleukin-13-109-a-a-rat-recombinant-protein-protp42203-boster.html

Gene Name :

Il13

Size :

2 ug, 10 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Description :

Interleukin-13 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 109 amino acids and having a molecular mass of 11.9 kDa. The IL-13 is purified by proprietary chromatographic techniques.

Source :

E. Coli

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

The protein (1mg/ml) was lyophilized in PBS, pH7.4.

AA Sequence and/or Biological Activity :

Amino Acid Sequence: VRRSTSPPVA LRELIEELSN ITQDQKTSLC NSSIVWSVDI TAGGFCAALE SLTNISSCNA IHRTQRILNG LCNQKASDVA SSPPDTKIEV AQFISKLLNY SKQLFRYGH.

Purification :

Greater than 95% as determined by SDS-PAGE.

Storage :

Lyophilized Interleukin-13 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL13 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P42203

Gene Full Name :

Interleukin-13

Synonyms :

Interleukin-13;IL-13;T-cell activation protein P600;Il13;Il-13;

Protein Function :

Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity).

Subcellular Localization :

Secreted.