IL-8 Interleukin-8 (1-77 a.a.) Human Recombinant Protein, (CXCL8) Pichia

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product summary

company name :

Boster

product type :

protein

product name :

IL-8 Interleukin-8 (1-77 a.a.) Human Recombinant Protein, (CXCL8) Pichia

catalog :

PROTP10145

quantity :

5 ug, 25 ug, 1 mg

product information

SKU :

PROTP10145

Product Name :

IL-8 Interleukin-8 (1-77 a.a.) Human Recombinant Protein, (CXCL8) Pichia

Product Page URL :

https://www.bosterbio.comil-8-interleukin-8-1-77-a-a-human-recombinant-protein-cxcl8-pichia-protp10145-boster.html

Gene Name :

CXCL8

Size :

5 ug, 25 ug, 1 mg

Introduction :

Introduction: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.

Description :

Interleukin-8 Human Recombinant produced in Yeast is a single, glycosylated polypeptide chain containing 79 amino acids and having a molecular mass of 9 kDa. The IL-8 is purified by proprietary chromatographic techniques.

Source :

Pichia Pastoris.

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

Lyophilized from a concentrated (1mg/ml) solution in water containing 20mM sodium phosphate buffer pH-8.

AA Sequence and/or Biological Activity :

Biological Activity:Specific Activity of IL8 in chemotaxis of donor PBL neutrophils, threshold concentration of 25ng/ml corresponding to a Specific Activity of 40,000IU/mg.

Purification :

Greater than 98.0% as determined by SDS-PAGE.

Storage :

Lyophilized Interleukin-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P10145

Synonyms :

Interleukin-8;IL-8;C-X-C motif chemokine 8;Chemokine (C-X-C motif) ligand 8;Emoctakin;Granulocyte chemotactic protein 1;GCP-1;Monocyte-derived neutrophil chemotactic factor;MDNCF;Monocyte-derived neutrophil-activating peptide;MONAP;Neutrophil-activating protein 1;NAP-1;Protein 3-10C;T-cell chemotactic factor;MDNCF-a;GCP/IL-8 protein IV;IL8/NAP1 form I;Interleukin-8; (Ala-IL-8)77;GCP/IL-8 protein II;IL-8 (1-77);IL8/NAP1 form II;MDNCF-b;IL-8 (5-77);IL-8 (6-77); (Ser-IL-8)72;GCP/IL-8 protein I;IL8/NAP1 form III;Lymphocyte-derived neutrophil-activating factor;LYNAP;MDNCF-c;Neutrophil-activating factor;NAF;IL-8 (7-77);GCP/IL-8 protein V;IL8/NAP1 form IV;IL-8 (8-77);GCP/IL-8 protein VI;IL8/NAP1 form V;IL-8 (9-77);GCP/IL-8 protein III;IL8/NAP1 form VI;CXCL8;IL8;