SRGN Serglycin Human Recombinant Protein | Boster PROTP10124 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

SRGN Serglycin Human Recombinant Protein

catalog :

PROTP10124

quantity :

5 ug, 20 ug, 1 mg

product information

sku :

PROTP10124

status :

Enabled

name :

SRGN Serglycin Human Recombinant Protein

gene name :

SRGN

price various sizes :

Sample: 5ug / $153 Regular: 20ug / $230 Bulk: 1mg / $2483

conjugate :

contents :

The SRGN solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.15M NaCl and 10% glycerol.

description :

SRGN Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 156 amino acids (28-158) and having a molecular mass of 17.4 kDa (Molecular weight on SDS-PAGE will appear higher). SRGN is fused to a 25 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.

short description :

description1 :

Introduction . SRGN is identified as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells also hold a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is related to the macromolecular complex of granzymes and perforin that acts as a intermediary of granule-mediated apoptosis.

description2 :

Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHMYPTRR ARYQWVRCNP DSNSANCLEE KGPMFELLPG ESNKIPRLRT DLFPKTRIQD LNRIFPLSED YSGSGFGSGS GSGSGSGSGF LTEMEQDYQL VDESDAFHDN LRSLDRNLPS DSQDLGQHGL EEDFML.

size :

5 ug, 20 ug, 1 mg

uniprot id :

P10124

host :

form :

Sterile Filtered colorless solution.

purification :

Greater than 90% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Serglycin;Hematopoietic proteoglycan core protein;Platelet proteoglycan core protein;P.PG;Secretory granule proteoglycan core protein;SRGN;PRG, PRG1;

gene full name :

Serglycin

protein function :

Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF- alpha and may also regulate protease secretion. Inhibits bone mineralization.

subcellular localization :

Cytoplasmic granule

source :

E.coli

last modified :

4/18/19 6:56